U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Phosphopantothenic acid is an amidoalkyl phosphate that is the 4-phosphate derivative of (R)-pantothenic acid. Phosphopantothenic acid is not permeable to cell membranes due to its anionic character, consistent with the observation that systemic administration of Phosphopantothenic acid does not restore CoA levels in cellular and mouse models

Approval Year

PubMed

PubMed

TitleDatePubMed
Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli.
2010-05-04
Kinetic characterization of human phosphopantothenoylcysteine synthetase.
2009-12
Selective inhibitors of bacterial phosphopantothenoylcysteine synthetase.
2009-11-18
Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action.
2009-04
Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis.
2009-03-31
Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor.
2004-03-16
Patents
Substance Class Mixture
Created
by admin
on Tue Apr 01 19:53:12 GMT 2025
Edited
by admin
on Tue Apr 01 19:53:12 GMT 2025
Record UNII
VA101M0K2F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FOSMETPANTOTENATE
INN   USAN  
USAN   INN  
Official Name English
fosmetpantotenate [INN]
Preferred Name English
FOSMETPANTOTENATE [USAN]
Common Name English
DIMETHYL 4-AMBO-(2S,8R)-8-HYDROXY-2,7,7-TRIMETHYL-4,9-DIOXO-4-PHENOXY-5-OXA-3,10-DIAZA-4.LAMBDA.5-PHOSPHATRIDECANEDIOATE
Systematic Name English
Fosmetpantotenate [WHO-DD]
Common Name English
RE-024
Code English
5-OXA-3,10-DIAZA-4-PHOSPHATRIDECANEDIOIC ACID, 8-HYDROXY-2,7,7-TRIMETHYL-9-OXO-4-PHENOXY-, 1,13-DIMETHYL ESTER, 4-OXIDE, (2S,8R)-
Systematic Name English
Classification Tree Code System Code
EU-Orphan Drug EU/3/16/1612
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C170010
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
PRIMARY
INN
10531
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
PRIMARY
USAN
DE-51
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
PRIMARY
FDA UNII
VA101M0K2F
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
PRIMARY
PUBCHEM
71811909
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
PRIMARY
CAS
1858268-66-2
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
PRIMARY
SMS_ID
100000178071
Created by admin on Tue Apr 01 19:53:12 GMT 2025 , Edited by admin on Tue Apr 01 19:53:12 GMT 2025
PRIMARY
All of the following components must be present:
Related Record Type Details
ACTIVE MOIETY
Definition References