PUTRESCINE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H12N2
Molecular Weight	88.1515
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

NCCCCN

InChI

InChIKey=KIDHWZJUCRJVML-UHFFFAOYSA-N

InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Protein-arginine N-methyltransferase 1 8	Inhibitor 8,504		35.0 mM [IC50]
Ornithine decarboxylase 15	Inhibitor 8,504

PubMed

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Title	Date	PubMed
Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction.	2000 Jul 21	10801782
Concomitant down-regulation of L-arginine transport and nitric oxide (NO) synthesis in rat alveolar macrophages by the polyamine spermine.	2001	11440558
Influence of heavy metals on the accumulation of trimethylglycine, putrescine and spermine in food plants.	2001	11354608
Possible implications of arginase and diamine oxidase in prostatic carcinoma.	2001	11270424
Structure-activity analysis of the potentiation by aminothiols of the chromosome-damaging effect of bleomycin in G0 human lymphocytes.	2001	11246218

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Patents

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Name

Type

Language

NSC-60545

Preferred Name

English

PUTRESCINE

Systematic Name

English

PUTRESCINE [MI]

Common Name

English

TETRAMETHYLENEDIAMINE

Systematic Name

English

1,4-BUTANEDIAMINE

Systematic Name

English

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Classification Tree

Code System

Code

Nitrogen Compound

NCI_THESAURUS

C759

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Code System

Code

Type

Description

DRUG BANK

DB01917

PRIMARY

MERCK INDEX

m9328

PRIMARY

Merck Index

CHEBI

326268

PRIMARY

NCI_THESAURUS

C129011

PRIMARY

FDA UNII

V10TVZ52E4

PRIMARY

Showing 1 to 5 of 14 entries

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ACTIVE MOIETY


					V10TVZ52E4

PUTRESCINE

SALT/SOLVATE (PARENT)


					X45SUR7RHY

PUTRESCINE DIHYDROCHLORIDE