PUTRESCINE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H12N2
Molecular Weight	88.1515
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PUTRESCINE

SMILES

NCCCCN

InChI

InChIKey=KIDHWZJUCRJVML-UHFFFAOYSA-N

InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2

HIDE SMILES / InChI

Molecular Formula	C4H12N2
Molecular Weight	88.1515
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Protein-arginine N-methyltransferase 1 8	Inhibitor 8,297		35.0 mM [IC50]
Ornithine decarboxylase 15	Inhibitor 8,297

PubMed

Show entries

Title	Date	PubMed
Roles of tissue transglutaminase in ethanol-induced inhibition of hepatocyte proliferation and alpha 1-adrenergic signal transduction.	2000 Jul 21	10801782
[(1)N,(12)N]Bis(Ethyl)-cis-6,7-dehydrospermine: a new drug for treatment and prevention of Cryptosporidium parvum infection of mice deficient in T-cell receptor alpha.	2000 Oct	10991882
Epithelial-mesenchymal interactions and lung branching morphogenesis. Role of polyamines and transforming growth factor beta1.	2001	11512636
Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse.	2001	11310560
Intestinal ornithine decarboxylase in short bowel syndrome patients with oral diet.	2001 Apr	11327746

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Patents

Substance Class	Chemical
Record UNII	V10TVZ52E4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PUTRESCINE

Systematic Name

English

NSC-60545

Code

English

PUTRESCINE [MI]

Common Name

English

TETRAMETHYLENEDIAMINE

Systematic Name

English

1,4-BUTANEDIAMINE

Systematic Name

English

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Classification Tree

Code System

Code

Nitrogen Compound

NCI_THESAURUS

C759

Showing 1 to 1 of 1 entries

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Code System

Code

Type

Description

DRUG BANK

DB01917

PRIMARY

MERCK INDEX

m9328

PRIMARY

Merck Index

CHEBI

326268

PRIMARY

NCI_THESAURUS

C129011

PRIMARY

FDA UNII

V10TVZ52E4

PRIMARY

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Related Record

Type

Details


					4Q83QF5K10

PUTRESCINE, C-11

LABELED -> NON-LABELED


					X45SUR7RHY

PUTRESCINE DIHYDROCHLORIDE

SALT/SOLVATE -> PARENT

Showing 1 to 2 of 2 entries

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Related Record

Type

Details


					V10TVZ52E4

ACTIVE MOIETY

Showing 1 to 1 of 1 entries