Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C15H22N2O17P2.2Na |
Molecular Weight | 610.2654 |
Optical Activity | ( + ) |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[H][C@]1(O[C@H](COP([O-])(=O)OP([O-])(=O)O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O)N3C=CC(=O)NC3=O
InChI
InChIKey=PKJQEQVCYGYYMM-QBNUFUENSA-L
InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL4518 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17088057 |
354.0 nM [EC50] | ||
Target ID: CHEMBL4714 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19902968 |
1600.0 nM [EC50] |
PubMed
Title | Date | PubMed |
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Biological functions of UDP-glucose synthesis in Streptococcus mutans. | 1998 May |
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Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs. | 2001 Dec |
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Active site residues and mechanism of UDP-glucose dehydrogenase. | 2004 Jan |
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The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. | 2006 Oct 4 |
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The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. | 2008 |
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Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems. | 2009 Jul |
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Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants. | 2010 Mar |
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Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. | 2015 Jun 5 |
Patents
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100000079795
Created by
admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
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DTXSID60182331
Created by
admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
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119803
Created by
admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
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UYD77NZ2JQ
Created by
admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
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28053-08-9
Created by
admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD