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Details

Stereochemistry ABSOLUTE
Molecular Formula C15H22N2O17P2.2Na
Molecular Weight 610.2654
Optical Activity ( + )
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of URIDINE 5'-DIPHOSPHOGLUCOSE DISODIUM

SMILES

[Na+].[Na+].[H][C@]1(O[C@H](COP([O-])(=O)OP([O-])(=O)O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O)N3C=CC(=O)NC3=O

InChI

InChIKey=PKJQEQVCYGYYMM-QBNUFUENSA-L
InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
354.0 nM [EC50]
1600.0 nM [EC50]
PubMed

PubMed

TitleDatePubMed
Biological functions of UDP-glucose synthesis in Streptococcus mutans.
1998 May
Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs.
2001 Dec
Active site residues and mechanism of UDP-glucose dehydrogenase.
2004 Jan
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.
2006 Oct 4
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.
2008
Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems.
2009 Jul
Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.
2010 Mar
Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.
2015 Jun 5
Patents

Patents

Name Type Language
URIDINE 5'-DIPHOSPHOGLUCOSE DISODIUM
Common Name English
Cogalactoisomerase sodium [WHO-DD]
Common Name English
DISODIUM UDP-GLUCOSE
Common Name English
COGALACTOISOMERASE SODIUM
Common Name English
URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-.ALPHA.-D-GLUCOPYRANOSYL ESTER, SODIUM SALT (1:2)
Systematic Name English
Code System Code Type Description
SMS_ID
100000079795
Created by admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
PRIMARY
EPA CompTox
DTXSID60182331
Created by admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
PRIMARY
PUBCHEM
119803
Created by admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
PRIMARY
FDA UNII
UYD77NZ2JQ
Created by admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
PRIMARY
CAS
28053-08-9
Created by admin on Sat Dec 16 18:11:08 GMT 2023 , Edited by admin on Sat Dec 16 18:11:08 GMT 2023
PRIMARY