URIDINE 5'-DIPHOSPHOGLUCOSE DISODIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H22N2O17P2.2Na
Molecular Weight	610.2654
Optical Activity	( + )
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of URIDINE 5'-DIPHOSPHOGLUCOSE DISODIUM

Structure Search

SMILES

[Na+].[Na+].[H][C@]1(O[C@H](COP([O-])(=O)OP([O-])(=O)O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O)N3C=CC(=O)NC3=O

InChI

InChIKey=PKJQEQVCYGYYMM-QBNUFUENSA-L

InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C15H22N2O17P2
Molecular Weight	564.2859
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Purinergic receptor P2Y14 5 Target ID: CHEMBL4518 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17088057	Agonist 2678		354.0 nM [EC50]
Pyrimidinergic receptor P2Y6 6 Target ID: CHEMBL4714 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19902968	Agonist 2678		1600.0 nM [EC50]

PubMed

Title	Date	PubMed
Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs.	2001 Dec	11735218
Active site residues and mechanism of UDP-glucose dehydrogenase.	2004 Jan	14686915
Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems.	2009 Jul	19339661
Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.	2010 Mar	20148890
Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.	2015 Jun 5	25526675

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:11:08 GMT 2023` Edited by `admin` on `Sat Dec 16 18:11:08 GMT 2023`
Record UNII	UYD77NZ2JQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

URIDINE 5'-DIPHOSPHOGLUCOSE DISODIUM

Common Name

English

Cogalactoisomerase sodium [WHO-DD]

Common Name

English

DISODIUM UDP-GLUCOSE

Common Name

English

COGALACTOISOMERASE SODIUM

Common Name

English

URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-.ALPHA.-D-GLUCOPYRANOSYL ESTER, SODIUM SALT (1:2)

Systematic Name

English

Code System Code Type Description

SMS_ID

100000079795