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Details

Stereochemistry ACHIRAL
Molecular Formula CH5N3S.ClH
Molecular Weight 127.596
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THIOSEMICARBAZIDE HYDROCHLORIDE

SMILES

Cl.NNC(N)=S

InChI

InChIKey=LEHOGBUBQSGCOK-UHFFFAOYSA-N
InChI=1S/CH5N3S.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Analgesic and anticonvulsant effects of extracts from the leaves of Kalanchoe crenata (Andrews) Haworth (Crassulaceae).
2006-06-15
Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi.
2006-06-01
Manganese(II) complexes of substituted di-2-pyridyl ketone thiosemicarbazones: structural and spectral studies.
2006-05-01
Bonding trends of thiosemicarbazones in mononuclear and dinuclear copper(I) complexes: syntheses, structures, and theoretical aspects.
2006-02-20
Rhodium assisted C-H activation of benzaldehyde thiosemicarbazones and their oxidation via activation of molecular oxygen.
2006-02-06
Synthesis of 5-phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic acid derivatives of potential anti-inflammatory activity.
2006-01
Benzoin 4-ethylthiosemicarbazone.
2006-01
Structural and spectral perspectives of a novel thiosemicarbazone synthesized from di-2-pyridyl ketone and 4-phenyl-3-thiosemicarbazide.
2006-01
Absolute configuration and conformational disorder of a tricyclic thiosemicarbazone derivative.
2005-12
Copper(II) complexes with substituted thiosemicarbazones of thiophene-2-carboxaldehyde: synthesis, characterization and antiamoebic activity against E. histolytica.
2005-12
Spectral studies of coordination compounds of cobalt(II) with thiosemicarbazone of heterocyclic ketone.
2005-12
Spectroscopic, cyclic voltammetric and biological studies of transition metal complexes with mixed nitrogen-sulphur (NS) donor macrocyclic ligand derived from thiosemicarbazide.
2005-11
Electrochemical and ESR study of 5-nitrofuryl-containing thiosemicarbazones antiprotozoal drugs.
2005-10
Chiral binaphthyl-derived amine-thiourea organocatalyst-promoted asymmetric Morita-Baylis-Hillman reaction.
2005-09-15
Antioxidant, pro-oxidant effect of the thiosemicarbazone derivative Schiff base (4-(1-phenylmethylcyclobutane-3-yl)-2-(2-hydroxybenzylidenehydrazino) thiazole) and its metal complexes on rats.
2005-09-07
Synthesis and spectroscopic study on photochromism of a new thiosemicarbazone compound containing pyrazolone.
2005-09
Controlled ligand deprotonation in lanthanide chelates with asymmetric semicarbazone/benzoylhydrazone or semicarbazone/thiosemicarbazone coordination spheres.
2005-08-08
Heterometallic compounds assembled from ferrocene-containing bisthiosemicarbazone clips.
2005-07-25
Nickel (II) complexes of naphthaquinone thiosemicarbazone and semicarbazone: synthesis, structure, spectroscopy, and biological activity.
2005-07
Thiourea-catalyzed enantioselective cyanosilylation of ketones.
2005-06-29
Synthesis and antiamoebic activity of 3,7-dimethyl-pyrazolo[3,4-e][1,2,4] triazin-4-yl thiosemicarbazide derivatives.
2005-06
Synthesis of thiosemicarbazone and 4-thiazolidinone derivatives and their in vitro anti-Toxoplasma gondii activity.
2005-05-16
Tetrazolo[1,5-a] quinoline derivatives as anti-inflammatory and antimicrobial agents [1].
2005-05-11
Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives.
2005-05-02
Synthesis and efficiency of a spherical macroporous epoxy-polyamide chelating resin for preconcentrating and separating trace noble metal ions.
2005-04-02
Physical and spectroscopic studies on novel vanadyl complexes of some substituted thiosemicarbazides.
2005-04
Benzimidazolyl quinolinyl mercaptotriazoles as potential antimicrobial and antiviral agents.
2005-03
Mono- and dinuclear tricarbonyltechnetium(I) complexes with thiosemicarbazones.
2005-02-21
Organometallic-based antibacterial and antifungal compounds: transition metal complexes of 1,1'-diacetylferrocene-derived thiocarbohydrazone, carbohydrazone, thiosemicarbazone and semicarbazone.
2005-02
Investigation into 64Cu-labeled Bis(selenosemicarbazone) and Bis(thiosemicarbazone) complexes as hypoxia imaging agents.
2005-02
Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.
2005-01-03
Spectroscopic, thermal and electrochemical studies on some nickel(II) thiosemicarbazone complexes.
2005-01-01
Structure and immunological activity of disubstituted thiosemicarbazide isoxazole derivative.
2004-12
Effects on rat testes of the thiosemicarbazone derivative Schiff base (4-(1-phenylmethylcyclobutane-3-yl)-2-(2-hydroxybenzylidenehydrazino)thiazole) and its cadmium(II) complex.
2004-11-13
Effect of bis(acetato)tetrakis(imidazole) copper(II) in delaying the onset and reducing the mortality rate of strychnine- and thiosemicarbazide- induced convulsions.
2004-10
Spectroscopic characterization of copper(II) complexes of indoxyl N(4)-methyl thiosemicarbazone.
2004-10
A phase I trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in combination with gemcitabine for patients with advanced cancer.
2004-10
In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.
2004-09-15
Syntheses and evaluation of antioxidant activity of sydnonyl substituted thiazolidinone and thiazoline derivatives.
2004-09-01
Synthesis and potential antimycotic activity of 4-substituted-3-(thiophene-2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones.
2004-09
Synthesis and antimicrobial activities of some new 1-(5-phenylamino-[1,3,4]thiadiazol-2-yl)methyl-5-oxo-[1,2,4]triazole and 1-(4-phenyl-5-thioxo-[1,2,4]triazol-3-yl)methyl-5-oxo- [1,2,4]triazole derivatives.
2004-09
Versatile chelating behavior of benzil bis(thiosemicarbazone) in zinc, cadmium, and nickel complexes.
2004-08-23
Incorporation of thiosemicarbazide in Amberlite IRC-50 for separation of astatine from alpha-irradiated bismuth oxide.
2004-06
Phase I and pharmacokinetic study of the ribonucleotide reductase inhibitor, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, administered by 96-hour intravenous continuous infusion.
2004-05-01
synthesis, characterization and in vitro antiamoebic activity of 5-nitrothiophene-2-carboxaldehyde thiosemicarbazones and their Palladium (II) and Ruthenium (II) complexes.
2004-05
Synthesis and pharmaceutical activity of new series of chromonyl derivatives.
2004-04-17
Synthesis and antioxidant properties of novel benzimidazole derivatives.
2004-04
A copper ion-selective electrode with high selectivity prepared by sol-gel and coated wire techniques.
2004-03
Stable gold(III) complexes with thiosemicarbazone derivatives.
2004-02-21
Inactivation of herpes simplex virus by thiosemicarbazones and certain cations.
1974-04
Patents
Name Type Language
NSC-191943
Preferred Name English
THIOSEMICARBAZIDE HYDROCHLORIDE
Common Name English
SEMICARBAZIDE, THIO-, MONOHYDROCHLORIDE
Common Name English
THIOSEMICARBAZIDE MONOHYDROCHLORIDE
Common Name English
HYDRAZINECARBOTHIOAMIDE, MONOHYDROCHLORIDE
Systematic Name English
Code System Code Type Description
CAS
4346-94-5
Created by admin on Wed Apr 02 12:15:24 GMT 2025 , Edited by admin on Wed Apr 02 12:15:24 GMT 2025
PRIMARY
EPA CompTox
DTXSID50195859
Created by admin on Wed Apr 02 12:15:24 GMT 2025 , Edited by admin on Wed Apr 02 12:15:24 GMT 2025
PRIMARY
PUBCHEM
3037943
Created by admin on Wed Apr 02 12:15:24 GMT 2025 , Edited by admin on Wed Apr 02 12:15:24 GMT 2025
PRIMARY
FDA UNII
UHX25R8M22
Created by admin on Wed Apr 02 12:15:24 GMT 2025 , Edited by admin on Wed Apr 02 12:15:24 GMT 2025
PRIMARY
NSC
191943
Created by admin on Wed Apr 02 12:15:24 GMT 2025 , Edited by admin on Wed Apr 02 12:15:24 GMT 2025
PRIMARY