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Details

Stereochemistry ACHIRAL
Molecular Formula C7H5NO4
Molecular Weight 167.1189
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,6-PYRIDINEDICARBOXYLIC ACID

SMILES

OC(=O)C1=CC=CC(=N1)C(O)=O

InChI

InChIKey=WJJMNDUMQPNECX-UHFFFAOYSA-N
InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3H,(H,9,10)(H,11,12)

HIDE SMILES / InChI

Description

2,6-Pyridinedicarboxylic acid (PDC, Dipicolinic acid) is a major component of bacterial endospores, comprising 5-15% of the spore dry weight, and is important for spore stability and resistance properties. 2,6-Pyridinedicarboxylic acid and its derivatives are introduced as a new sensitizer system for enzyme-amplified lanthanide luminescence (EALL), a detection scheme for bioassays, which combines enzymatic amplification with time-resolved luminescence measurements of lanthanide chelates.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
7.8 µM [IC50]
41.6 µM [IC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Other
In Vitro Use Guide
Amino acid appearance/disappearance 'profiles' of single bovine blastocysts were determined at 0, 1.25 and 2.5 mM NH(4)Cl (with or without 0.33 mM pyruvate), and with or without 10 mM dipicolinic acid (DPCA; a glutamate dehydrogenase (GLDH) inhibitor) or 2 mM amino-oxyacetate (AOA; a transaminase inhibitor).