Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H5NO4 |
| Molecular Weight | 167.1189 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=CC=CC(=N1)C(O)=O
InChI
InChIKey=WJJMNDUMQPNECX-UHFFFAOYSA-N
InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3H,(H,9,10)(H,11,12)
| Molecular Formula | C7H5NO4 |
| Molecular Weight | 167.1189 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
2,6-Pyridinedicarboxylic acid (PDC, Dipicolinic acid) is a major component of bacterial endospores, comprising 5-15% of the spore dry weight, and is important for spore stability and resistance properties. 2,6-Pyridinedicarboxylic acid and its derivatives are introduced as a new sensitizer system for enzyme-amplified lanthanide luminescence (EALL), a detection scheme for bioassays, which combines enzymatic amplification with time-resolved luminescence measurements of lanthanide chelates.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Fluorescence assays for liposome fusion. | 2003 |
|
| Germination of spores of Bacillus subtilis with dodecylamine. | 2003 |
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| Mechanisms of killing of Bacillus subtilis spores by hypochlorite and chlorine dioxide. | 2003 |
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| The determination of the stability constant for the iron(II) complex of the biochelator pyridine-2,6-bis(monothiocarboxylic acid). | 2003 Apr |
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| Analysis of carboxylic acid metabolites from the tricarboxylic acid cycle in Bacillus subtilis cell extract by capillary electrophoresis using an indirect photometric detection method. | 2003 Aug 22 |
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| Spore germination. | 2003 Dec |
|
| Kinetics and mechanistic studies of anticarcinogenic bisperoxovanadium(V) compounds: ligand substitution reactions at physiological pH and relevance to DNA interactions. | 2003 Dec 1 |
|
| Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators. | 2003 Dec 12 |
|
| Coexistence of water dimer and hexamer clusters in 3D metal-organic framework structures of Ce(III) and Pr(III) with pyridine-2,6-dicarboxylic acid. | 2003 Dec 15 |
|
| Native fluorescence and excitation spectroscopic changes in Bacillus subtilis and Staphylococcus aureus bacteria subjected to conditions of starvation. | 2003 Jul 1 |
|
| Self-referencing intensity measurements based on square-wave gated phase-modulation fluorimetry. | 2003 May |
|
| Bacterial spore germination and protein mobility. | 2003 Oct |
|
| Laser power dependence of mass spectral signatures from individual bacterial spores in bioaerosol mass spectrometry. | 2003 Oct 15 |
|
| High-performance capillary electrophoresis with indirect UV detection for determination of alpha-galactosides in Leguminosae and Brassicaceae. | 2003 Oct 22 |
|
| An ultrastructural comparison of spores from various strains of Clostridium perfringens and correlations with heat resistance parameters. | 2003 Sep 15 |
|
| The three-dimensional structures of the Mycobacterium tuberculosis dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes. Structural and mutagenic analysis of relaxed nucleotide specificity. | 2003 Sep 16 |
|
| Reactions of the dirhenium(II) complex Re2Cl4(mu-dppm)2 with pyridinecarboxylic acids. Examples of bidentate O,O versus N,O coordination and tridentate O,N,O coordination and structural isomers that contain the pyridine-2,6-dicarboxylate ligand. | 2003 Sep 22 |
|
| Effect of microwave radiation on Bacillus subtilis spores. | 2004 |
|
| Treatment with oxidizing agents damages the inner membrane of spores of Bacillus subtilis and sensitizes spores to subsequent stress. | 2004 |
|
| Mechanisms of Bacillus subtilis spore resistance to and killing by aqueous ozone. | 2004 |
|
| Mechanisms of killing of Bacillus subtilis spores by Decon and Oxone, two general decontaminants for biological agents. | 2004 |
|
| Solid state characterization of oligopyridine dicarboxamide helicates. | 2004 Apr 21 |
|
| Copper dipicolinates as peptidomimetic ligands for the Src SH2 domain. | 2004 Aug 16 |
|
| Intensities of calcium dipicolinate and Bacillus subtilis spore Raman spectra excited with 244 nm light. | 2004 Dec |
|
| Coordination polymers containing 1D channels as selective luminescent probes. | 2004 Dec 1 |
|
| Linear rheology of water-soluble reversible neodymium(III) coordination polymers. | 2004 Dec 8 |
|
| Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site. | 2004 Feb 10 |
|
| Speciation of inorganic and methylated arsenic compounds by capillary zone electrophoresis with indirect UV detection. Application to the analysis of alkali extracts of As2S2 (realgar) and As2S3 (orpiment). | 2004 Feb 13 |
|
| Ammonium exposure and pyruvate affect the amino acid metabolism of bovine blastocysts in vitro. | 2004 Jan |
|
| Penipratynolene, a novel nematicide from penicillium bilaiae Chalabuda. | 2004 Jan |
|
| Retention of Cr(III) by high-performance chelation ion chromatography interfaced to inductively-coupled plasma mass spectrometric detection with collision cell. | 2004 Jan 23 |
|
| On-column complexation capillary electrophoretic separation of Fe2+ and Fe3+ using 2,6-pyridinedicarboxylic acid coupled with large-volume sample stacking. | 2004 Jan 9 |
|
| Bis(mu-6-hydroxypicolinato)-mu-oxo-bis[dipyridinemanganese(III)] monohydrate. | 2004 Jul |
|
| Functional and biochemical characterization of a recombinant Arabidopsis thaliana 3-deoxy-D-manno-octulosonate 8-phosphate synthase. | 2004 Jul 1 |
|
| Toward understanding the ionization of biomarkers from micrometer particles by bio-aerosol mass spectrometry. | 2004 Jun |
|
| Rapid dipicolinic acid extraction from Bacillus spores detected by surface-enhanced Raman spectroscopy. | 2004 Mar |
|
| Quantitative spectroscopy analysis of prokaryotic cells: vegetative cells and spores. | 2004 Mar 15 |
|
| New pyridine carboxamide ligands and their complexation to copper(II). X-Ray crystal structures of mono-, di, tri- and tetranuclear copper complexes. | 2004 Mar 21 |
|
| Octanuclear and nonanuclear supramolecular copper(II) complexes with linear "tritopic" ligands: structural and magnetic studies. | 2004 Mar 22 |
|
| Steady-state and frequency-domain lifetime measurements of an activated molecular imprinted polymer imprinted to dipicolinic acid. | 2004 May |
|
| Selective complexation and transport of europium ions at the interface of vesicles. | 2004 May 3 |
|
| Mid-ultraviolet light-emitting diode detects dipicolinic acid. | 2004 Nov |
|
| 10-membered macrolides from the insect pathogenic fungus Cordyceps militaris BCC 2816. | 2004 Nov |
|
| Comparison of pressure and heat resistance of Clostridium botulinum and other endospores in mashed carrots. | 2004 Nov |
|
| Capillary electrophoresis of the major anions and cations in leaf extracts of woody species. | 2004 Nov-Dec |
|
| Enzymatic determination of zinc in vegetables using apocarbonic anhydrase. | 2004 Nov-Dec |
|
| Analysis of the germination of spores of Bacillus subtilis with temperature sensitive spo mutations in the spoVA operon. | 2004 Oct 1 |
|
| Characterization of a polysaccharide deacetylase gene homologue (pdaB) on sporulation of Bacillus subtilis. | 2004 Sep |
|
| Amperometric hydrogen peroxide biosensor based on horseradish peroxidase-labeled nano-Au colloids immobilized on poly(2,6-pyridinedicarboxylic acid) layer by cysteamine. | 2004 Sep |
|
| Bis(micro-ethyl pyridine-2,6-dicarboxylato)bis[diaquachlorocadmium(II)] dihydrate. | 2004 Sep |
Sample Use Guides
Amino acid appearance/disappearance 'profiles' of single bovine blastocysts were determined at 0, 1.25 and 2.5 mM NH(4)Cl (with or without 0.33 mM pyruvate), and with or without 10 mM dipicolinic acid (DPCA; a glutamate dehydrogenase (GLDH) inhibitor) or 2 mM amino-oxyacetate (AOA; a transaminase inhibitor).
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:05:06 UTC 2023
by
admin
on
Fri Dec 15 19:05:06 UTC 2023
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| Record UNII |
UE81S5CQ0G
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| Record Status |
Validated (UNII)
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| Record Version |
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Food Contact Sustance Notif, (FCN No.) |
FCN NO. 1094
Created by
admin on Fri Dec 15 19:05:06 UTC 2023 , Edited by admin on Fri Dec 15 19:05:06 UTC 2023
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Food Contact Sustance Notif, (FCN No.) |
FCN NO. 1025
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admin on Fri Dec 15 19:05:06 UTC 2023 , Edited by admin on Fri Dec 15 19:05:06 UTC 2023
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Food Contact Sustance Notif, (FCN No.) |
FCN NO. 1035
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admin on Fri Dec 15 19:05:06 UTC 2023 , Edited by admin on Fri Dec 15 19:05:06 UTC 2023
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DIPICOLINIC ACID
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