PRODOLIC ACID

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H19NO3
Molecular Weight	273.327
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCC1(CC(O)=O)OCCC2=C1NC3=C2C=CC=C3

InChI

InChIKey=IZGMROSLQHXRDZ-UHFFFAOYSA-N

InChI=1S/C16H19NO3/c1-2-8-16(10-14(18)19)15-12(7-9-20-16)11-5-3-4-6-13(11)17-15/h3-6,17H,2,7-10H2,1H3,(H,18,19)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/925966 | https://www.ncbi.nlm.nih.gov/pubmed/305689 | https://www.ncbi.nlm.nih.gov/pubmed/1139444

Prodolic acid is an indole derivative patented by American Home Products Corp. as antiinflammatory agent. Prodolic acid acts as non-steroidal anti-inflammatory compound and inhibits bradykinin-induced bronchoconstriction but did not affects histamine-induced bronchoconstriction in the guinea pig. In preclinical studies, Prodolic acid exhibits potent anti-inflammatory activity in adjuvant arthritic rats.

Originator

Approval Year

PubMed

Title	Date	PubMed
Chemistry and antiinflammatory activities of prodolic-acid and related 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-alkanoic acids. 1.	1975 Feb	1120985

Patents

Name

Type

Language

PRODOLIC ACID

Official Name

English

1,3,4,9-Tetrahydro-1-propylpyrano[3,4-b]indole-1-acetic acid

Systematic Name

English

prodolic acid [INN]

Common Name

English

PYRANO(3,4-B)INDOLE-1-ACETIC ACID, 1,3,4,9-TETRAHYDRO-1-PROPYL-

Systematic Name

English

AY-23289

Code

English

NSC-299133

Code

English

AY-23,289

Code

English

PRODOLIC ACID [USAN]

Common Name

English

Code System Code Type Description

PUBCHEM

37462