U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C14H13NO2
Molecular Weight 227.2585
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIPHENAN

SMILES

NC(=O)OC1=CC=C(CC2=CC=CC=C2)C=C1

InChI

InChIKey=ZBJBRUSGEJORQL-UHFFFAOYSA-N
InChI=1S/C14H13NO2/c15-14(16)17-13-8-6-12(7-9-13)10-11-4-2-1-3-5-11/h1-9H,10H2,(H2,15,16)

HIDE SMILES / InChI
Diphenan is p-benzyl-phenyl-carbamate. Various workers have reported that diphenan will rid children of oxyurids and it has been claimed to be nontoxic and tasteless and to have the advantage of being a vermicide as opposed to a vermifuge. An attempt has been made to assess the efficacy of diphenan as a vermicide. Diphenan was given far in excess of the normal dosage. Subsequent examnation showed few cures and these mostly in lightly infested children. The condition of many was unchanged and that of some worse after treatment. No toxic reactions were encountered. Moreover, diphenan was found to have no detectable anthelmintic effect when given in high dosage in the treatment of enterobiasis.

Approval Year

Patents

Patents

Sample Use Guides

0.5-1 g thrice daily for 10 successive days.
Route of Administration: Oral
Name Type Language
DIPHENAN
INN  
INN  
Official Name English
diphenan [INN]
Common Name English
.ALPHA.-PHENYL-P-CRESOL CARBAMATE
Common Name English
NSC-60023
Code English
GNF-PF-1544
Code English
DIPHENANE [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C250
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID4046234
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
SMS_ID
100000082878
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
PUBCHEM
7572
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
CAS
101-71-3
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
MERCK INDEX
m150
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY Merck Index
FDA UNII
U129BBY8DB
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
NSC
60023
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
DRUG CENTRAL
3736
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
ChEMBL
CHEMBL608856
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
EVMPD
SUB07210MIG
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
INN
48
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY
NCI_THESAURUS
C65420
Created by admin on Fri Dec 15 16:21:22 GMT 2023 , Edited by admin on Fri Dec 15 16:21:22 GMT 2023
PRIMARY