U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Name Type Language
Efdoralprin Alfa
INN  
Official Name English
IgG4 Fc linked recombinant human alpha-1 antitrypsin
Preferred Name English
?1-Antitrypsin [351-glutamic acid,358-leucine] (human) fusion protein with peptide linker (GS) fusion protein with immunoglobulin G4 [406-proline,413-glutamic acid,430-tyrosine,606-leucine] (human ?4-chain C region C-terminal fragment), dimer
Common Name English
efdoralprin alfa [INN]
Common Name English
human alpha-1-antitrypsin (alpha-1 protease inhibitor, serpin A1, AAT) (1-394), variant (M<sup>351</sup>>E, M<sup>358</sup>>L) fused via peptide linker <sup>395</sup>GS<sup>396</sup> to an Fc fragment of human immunoglobulin G4 (397-625) [Homo sapiens IG
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 863521
Created by admin on Wed Apr 02 05:30:28 GMT 2025 , Edited by admin on Wed Apr 02 05:30:28 GMT 2025
Code System Code Type Description
SMS_ID
300000027211
Created by admin on Wed Apr 02 05:30:28 GMT 2025 , Edited by admin on Wed Apr 02 05:30:28 GMT 2025
PRIMARY
INN
13115
Created by admin on Wed Apr 02 05:30:28 GMT 2025 , Edited by admin on Wed Apr 02 05:30:28 GMT 2025
PRIMARY
FDA UNII
TYK0A4WR1D
Created by admin on Wed Apr 02 05:30:28 GMT 2025 , Edited by admin on Wed Apr 02 05:30:28 GMT 2025
PRIMARY
NCI_THESAURUS
C211809
Created by admin on Wed Apr 02 05:30:28 GMT 2025 , Edited by admin on Wed Apr 02 05:30:28 GMT 2025
PRIMARY
CAS
2539844-42-1
Created by admin on Wed Apr 02 05:30:28 GMT 2025 , Edited by admin on Wed Apr 02 05:30:28 GMT 2025
PRIMARY
NIH
NCATS
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