Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H16N2O |
| Molecular Weight | 228.2896 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC1=C(CC2=NCCN2)C3=C(O1)C=CC=C3
InChI
InChIKey=QZRIKRJFJVVUSF-UHFFFAOYSA-N
InChI=1S/C14H16N2O/c1-2-12-11(9-14-15-7-8-16-14)10-5-3-4-6-13(10)17-12/h3-6H,2,7-9H2,1H3,(H,15,16)
Coumazoline is a vasoconstrictor developed as a nasal decongestant by a French corporation Labez. Intravenous administration of the compound to dogs lead to a marked and prolonged drop in the temperature of the gingival mucosa. In rats, coumazoline caused slowing of the dye diffusion on the surface of the skin. The compound did not influence the ciliary motility, as was measured on an isolated guinea pig trachea.
Approval Year
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NCI_THESAURUS |
C29709
Created by
admin on Fri Dec 15 16:10:40 GMT 2023 , Edited by admin on Fri Dec 15 16:10:40 GMT 2023
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100000083735
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TR7Y641235
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CHEMBL2106000
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3134
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37681-00-8
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SUB06815MIG
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C007141
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C79706
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37808
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DTXSID50191114
Created by
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ACTIVE MOIETY
