U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C18H25Cl3O2
Molecular Weight 379.749
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of K-111

SMILES

OC(=O)C(Cl)(Cl)CCCCCCCCCCC1=CC=C(Cl)C=C1

InChI

InChIKey=GPCJDSXBRMKASP-UHFFFAOYSA-N
InChI=1S/C18H25Cl3O2/c19-16-12-10-15(11-13-16)9-7-5-3-1-2-4-6-8-14-18(20,21)17(22)23/h10-13H,1-9,14H2,(H,22,23)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
BM 17.0744: a structurally new antidiabetic compound with insulin-sensitizing and lipid-lowering activity.
1999 Jan
Peroxisome proliferator-activated receptor-alpha ligands inhibit cardiac lipoprotein lipase activity.
2001 Aug
The effects of K-111, a new insulin-sensitizer, on metabolic syndrome in obese prediabetic rhesus monkeys.
2003 Oct
Human adipocyte fatty acid-binding protein (aP2) gene promoter-driven reporter assay discriminates nonlipogenic peroxisome proliferator-activated receptor gamma ligands.
2004 Nov
Drug evaluation: K-111, an insulin-sensitizing peroxisome proliferator-activated receptor alpha agonist.
2007 Apr
Patents

Patents

Name Type Language
K-111
Code English
K111
Code English
K111 (PHARMACEUTICAL)
Code English
.ALPHA.,.ALPHA.,4-TRICHLOROBENZENEDODECANOIC ACID
Common Name English
BM-17.0744
Code English
BM170744
Code English
BM-170744
Code English
BENZENEDODECANOIC ACID, .ALPHA.,.ALPHA.,4-TRICHLORO-
Systematic Name English
2,2-DICHLORO-12-(4-CHLOROPHENYL)DODECANOIC ACID
Systematic Name English
Code System Code Type Description
CAS
221564-97-2
Created by admin on Sat Dec 16 18:02:22 GMT 2023 , Edited by admin on Sat Dec 16 18:02:22 GMT 2023
PRIMARY
FDA UNII
TM9XQR923G
Created by admin on Sat Dec 16 18:02:22 GMT 2023 , Edited by admin on Sat Dec 16 18:02:22 GMT 2023
PRIMARY
EPA CompTox
DTXSID901286589
Created by admin on Sat Dec 16 18:02:22 GMT 2023 , Edited by admin on Sat Dec 16 18:02:22 GMT 2023
PRIMARY
PUBCHEM
9929731
Created by admin on Sat Dec 16 18:02:22 GMT 2023 , Edited by admin on Sat Dec 16 18:02:22 GMT 2023
PRIMARY