U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C31H32N4O2.ClH
Molecular Weight 529.072
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BEZITRAMIDE HYDROCHLORIDE

SMILES

Cl.CCC(=O)N1C(=O)N(C2CCN(CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=C1C=CC=C5

InChI

InChIKey=AJSZDJPJGGMSPW-UHFFFAOYSA-N
InChI=1S/C31H32N4O2.ClH/c1-2-29(36)35-28-16-10-9-15-27(28)34(30(35)37)26-17-20-33(21-18-26)22-19-31(23-32,24-11-5-3-6-12-24)25-13-7-4-8-14-25;/h3-16,26H,2,17-22H2,1H3;1H

HIDE SMILES / InChI
Bezitramide was developed as an orally long-acting analgesic compound and was marketed under the brand name Burgodin. The overdose of this drug caused death that is why it was withdrawn from the market.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Burgodin

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Bezitramide, an orally active analgesic. An investigation on pain following operations for lumbar disc protrusion (preliminary report).
1970 Apr
Effects of bezafibrate and simvastatin on endothelial activation and lipid peroxidation in hypercholesterolemia: evidence of different vascular protection by different lipid-lowering treatments.
2003 Nov
The use of driving impairing medicines: a European survey.
2009 Nov
Patents

Patents

Sample Use Guides

5 mg
Route of Administration: Oral
Name Type Language
BEZITRAMIDE HYDROCHLORIDE
Common Name English
2H-BENZIMIDAZOL-2-ONE, 1-(1-(3-CYANO-3,3-DIPHENYLPROPYL)-4-PIPERIDINYL)-1,3-DIHYDRO-3-(1-OXOPROPYL)-, MONOHYDROCHLORIDE
Common Name English
BEZITRAMIDE-HYDROCHLORIDE
Common Name English
1-PIPERIDINEBUTANENITRILE, 4-(2,3-DIHYDRO-2-OXO-3-(1-OXOPROPYL)-1H-BENZIMIDAZOL-1-YL)-.ALPHA.,.ALPHA.-DIPHENYL-, HYDROCHLORIDE (1:1)
Systematic Name English
Code System Code Type Description
PUBCHEM
145996662
Created by admin on Sat Dec 16 11:32:41 GMT 2023 , Edited by admin on Sat Dec 16 11:32:41 GMT 2023
PRIMARY
FDA UNII
TAB8WY5HVX
Created by admin on Sat Dec 16 11:32:41 GMT 2023 , Edited by admin on Sat Dec 16 11:32:41 GMT 2023
PRIMARY
CAS
59708-44-0
Created by admin on Sat Dec 16 11:32:41 GMT 2023 , Edited by admin on Sat Dec 16 11:32:41 GMT 2023
PRIMARY