DAZADROL MALEATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H14ClN3O.C4H4O4
Molecular Weight	403.816
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)\C=C/C(O)=O.OC(C1=NCCN1)(C2=CC=C(Cl)C=C2)C3=NC=CC=C3

InChI

InChIKey=UFDGEMYZSPSGFD-BTJKTKAUSA-N

InChI=1S/C15H14ClN3O.C4H4O4/c16-12-6-4-11(5-7-12)15(20,14-18-9-10-19-14)13-3-1-2-8-17-13;5-3(6)1-2-4(7)8/h1-8,20H,9-10H2,(H,18,19);1-2H,(H,5,6)(H,7,8)/b;2-1-

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4393004

Dazadrol is an antidepressant compound, developed by Schering Corp in the late 1960s. Dazadrol blocks uptake of noradrenaline and inhibits both basal and induced gastric acid secretion in the rat.

Originator

Approval Year

PubMed

Title	Date	PubMed
Blockade of noradrenaline uptake and inhibition of gastric acid secretion by 2-[p-chlorophenyl-2-(pyridyl)hydroxymethyl] imidazoline maleate (Sch-12650).	1970-05	4393004

Patents

Name

Type

Language

SCH 12650

Preferred Name

English

DAZADROL MALEATE

Official Name

English

2-PYRIDINEMETHANOL, .ALPHA.-(4-CHLOROPHENYL)-.ALPHA.-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-, (Z)-2-BUTENEDIOATE (1:1) (SALT)

Common Name

English

DAZADROL MALEATE [USAN]

Common Name

English

.ALPHA.-(P-CHLOROPHENYL)-.ALPHA.-2-IMIDAZOLIN-2-YL-2-PYRIDINEMETHANOL MALEATE (1:1) (SALT)

Common Name

English

SCH-12650

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C265