Opemalirsen

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

Opemalirsen

Official Name

English

AZD-2373

Preferred Name

English

opemalirsen [INN]

Common Name

English

all-P-ambo-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiouridylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiouridylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiouridylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl

Common Name

English

OPEMALIRSEN [USAN]

Common Name

English

DNA, d(P-thio)([2?,5?-anhydro-6?-deoxy-4?-C-(hydroxymethyl)-?-L-mannofurano]m5rU-(3??4?)-[2?,5?-anhydro-6?-deoxy-4?-C-(hydroxymethyl)-?-L-mannofurano]m5rU-(3??4?)-[2?,5?-anhydro-6?-deoxy-4?-C-(hydroxymethyl)-?-L-mannofurano](3??4?)m5rU-T-G-T-A-A-G-T-G-m5

Common Name

English

AZD2373

Code

English

ION-972190

Code

English

Code System Code Type Description

NCI_THESAURUS

C203038

Created by admin on Wed Apr 02 06:00:23 GMT 2025 , Edited by admin on Wed Apr 02 06:00:23 GMT 2025

PRIMARY

CAS

2639853-99-7

Created by admin on Wed Apr 02 06:00:23 GMT 2025 , Edited by admin on Wed Apr 02 06:00:23 GMT 2025

PRIMARY

USAN

MN-242

Created by admin on Wed Apr 02 06:00:23 GMT 2025 , Edited by admin on Wed Apr 02 06:00:23 GMT 2025

PRIMARY

INN

12631

Created by admin on Wed Apr 02 06:00:23 GMT 2025 , Edited by admin on Wed Apr 02 06:00:23 GMT 2025

PRIMARY

FDA UNII

SVT2GC4GOI

Created by admin on Wed Apr 02 06:00:23 GMT 2025 , Edited by admin on Wed Apr 02 06:00:23 GMT 2025

PRIMARY

SMS_ID

300000052413

Created by admin on Wed Apr 02 06:00:23 GMT 2025 , Edited by admin on Wed Apr 02 06:00:23 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_4-1_12	9 / 16
	1_1-1_3;1_13-1_15	6 / 16
2'-O-Methoxyethyl ribose	1_16	1 / 16

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_16	15 / 15

ACTIVE MOIETY


					SVT2GC4GOI