Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C23H25F3N4O5 |
| Molecular Weight | 494.4636 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C=C(N=C1C2=CC=C(OCC(O)CNCCOC3=CC=C(O)C(=C3)C(N)=O)C=C2)C(F)(F)F
InChI
InChIKey=GKJZEKSHCJELPL-UHFFFAOYSA-N
InChI=1S/C23H25F3N4O5/c1-30-12-20(23(24,25)26)29-22(30)14-2-4-16(5-3-14)35-13-15(31)11-28-8-9-34-17-6-7-19(32)18(10-17)21(27)33/h2-7,10,12,15,28,31-32H,8-9,11,13H2,1H3,(H2,27,33)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Atypical beta-adrenergic receptor in 3T3-F442A adipocytes. Pharmacological and molecular relationship with the human beta 3-adrenergic receptor. | 1991 Oct 25 |
|
| Pre- and postganglionic stimulation-induced noradrenaline overflow is markedly facilitated by a prejunctional beta 2-adrenoceptor-mediated control mechanism in the pithed rat. | 1994 Jun |
|
| Carazolol: a potent, selective beta 3-adrenoceptor agonist. | 1995 Nov 30 |
|
| Selective activation of beta3-adrenoceptors by octopamine: comparative studies in mammalian fat cells. | 1999 Apr |
|
| Potent and selective human beta(3)-adrenergic receptor antagonists. | 1999 Aug |
|
| LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors. | 1999 Feb 19 |
|
| Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein. | 1999 Nov 30 |
|
| Constitutive activity of the human beta(1)-adrenergic receptor in beta(1)-receptor transgenic mice. | 2001 Oct |
|
| Bone marrow-derived regenerated cardiomyocytes (CMG Cells) express functional adrenergic and muscarinic receptors. | 2002 Jan 22 |
|
| Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. | 2004 Feb |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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2685
Created by
admin on Sat Dec 16 09:51:51 UTC 2023 , Edited by admin on Sat Dec 16 09:51:51 UTC 2023
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SIO2UEZ19H
Created by
admin on Sat Dec 16 09:51:51 UTC 2023 , Edited by admin on Sat Dec 16 09:51:51 UTC 2023
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81015-67-0
Created by
admin on Sat Dec 16 09:51:51 UTC 2023 , Edited by admin on Sat Dec 16 09:51:51 UTC 2023
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SUPERSEDED | |||
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137888-49-4
Created by
admin on Sat Dec 16 09:51:51 UTC 2023 , Edited by admin on Sat Dec 16 09:51:51 UTC 2023
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PRIMARY | |||
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DTXSID301001709
Created by
admin on Sat Dec 16 09:51:51 UTC 2023 , Edited by admin on Sat Dec 16 09:51:51 UTC 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SALT/SOLVATE (PARENT)
