Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C5H7NO4.Mg.2H.4H2O |
| Molecular Weight | 388.6088 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H+].[H+].O.O.O.O.[Mg++].N[C@@H](CCC([O-])=O)C([O-])=O.N[C@@H](CCC([O-])=O)C([O-])=O
InChI
InChIKey=ZWCGDRSVJYJGFY-GYDBBPQESA-L
InChI=1S/2C5H9NO4.Mg.4H2O/c2*6-3(5(9)10)1-2-4(7)8;;;;;/h2*3H,1-2,6H2,(H,7,8)(H,9,10);;4*1H2/q;;+2;;;;/p-2/t2*3-;;;;;/m00...../s1
DescriptionSources: https://noshly.com/additive/e625/flavour-enhancer/625/ | http://www.thegoodscentscompany.com/data/rw1609401.html | http://www.foodadditiveslist.com/page/55/ | http://www.fao.org/ag/agn/jecfa-additives/specs/Monograph1/Additive-259.pdfhttps://www.ncbi.nlm.nih.gov/pubmed/680616 | http://www.druginfosys.com/drug.aspx?drugcode=1321&type=1
Sources: https://noshly.com/additive/e625/flavour-enhancer/625/ | http://www.thegoodscentscompany.com/data/rw1609401.html | http://www.foodadditiveslist.com/page/55/ | http://www.fao.org/ag/agn/jecfa-additives/specs/Monograph1/Additive-259.pdfhttps://www.ncbi.nlm.nih.gov/pubmed/680616 | http://www.druginfosys.com/drug.aspx?drugcode=1321&type=1
Magnesium glutamate hydrobromide (Psychoverlan) is a known sedative and muscle relaxant. In a long-term study 19 young females were treated with Psychoverlan capsules or syrup for an average of 11.4 months. Intolerance phenomena and side-effects were not seen. It was even decided to increase the standard dose. None of the patients developed brominism or bromine intoxication. The general state of health of 13 of the 19 subjects was improved by the harmonizing effect of the drug on psychic and vegetative functions. Tiredness and somnolence were not observed.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Synthesis and biological evaluation of (-)-6-O-desmethylcryptopleurine and analogs. | 2015-01-15 |
|
| No enhancing effects of calcium/magnesium salts of L-glutamate and L-ascorbate on tumor development in a rat medium-term multiorgan carcinogenesis bioassay. | 1993-05 |
|
| [Long-term treatment with psychoverlan in children and adolescents with behavior disorders]. | 1978-08-24 |
|
| [The management of nervous disturbances with psychoverlan]. | 1974-05 |
Sample Use Guides
In Vivo Use Guide
Curator's Comment: Rats were given diet containing 5% monocalcium di-L-glutamate tetrahydrate (Ca-glutamate), 2.5% monomagnesium di-L-glutamate tetrahydrate (Mg-glutamate), 5% L-glutamic acid, 5% monocalcium di-L-ascorbate dihydrate (Ca-ascorbate), 2.5% monomagnesium di-L-ascorbate dihydrate (Mg-ascorbate), or 5% L-ascorbic acid for 16 wk.
Unknown
Route of Administration:
Oral
60 g (0.160 mol) magnesium-L-glutamate-tetrahydrate in a spherical flask were suhmerged in the rotary evaporator under a vacuum of 50 mbar in an oil bath that had been preheated to 190C. The separation of water and the formation of the magnesium-L-pyroglutamate began after 2 minutes and ended after 45 minutes, a solid being involved at each stage of the reaction.
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129160-51-6
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INS-625
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SUB68830
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100000134894
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SUBSTANCE RECORD
