Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C27H36N2O4 |
| Molecular Weight | 452.5857 |
| Optical Activity | ( - ) |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)C1=CC(CCN(C)CCC[C@](C#N)(C(C)C)C2=CC=C(OC)C(OC)=C2)=CC=C1
InChI
InChIKey=VAZNEHLGJGSQEL-MHZLTWQESA-N
InChI=1S/C27H36N2O4/c1-20(2)27(19-28,23-11-12-24(31-4)25(18-23)32-5)14-8-15-29(3)16-13-21-9-7-10-22(17-21)26(30)33-6/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t27-/m0/s1
Etripamil is a non-dihydropyridine, L-type calcium channel blocker. Currently, etripamil is in Phase 3 development for the treatment of paroxysmal supraventricular tachycardia. Milestone Pharmaceuticals is also developing etripamil to provide rapid heartbeat control for patients living with atrial fibrillation and acute symptom relief for patients with angina.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Etripamil: Self-management of supraventricular tachycardia is not far away? | 2019-03 |
|
| Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. | 2018-07-31 |
|
| High-density mapping of the slow pathway in a patient with atrioventricular nodal reentry given intranasal Etripamil during the NODE-1 study. | 2017-10 |
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S82A18Y42P
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CHEMBL3707312
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10134
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300000003780
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DB12605
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1593673-23-4
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CD-171
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C169972
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ACTIVE MOIETY
