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Details

Stereochemistry ACHIRAL
Molecular Formula C3H9N3S
Molecular Weight 119.189
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-MERCAPTOETHYLGUANIDINE

SMILES

NC(=N)NCCS

InChI

InChIKey=GAPFINWZKMCSBG-UHFFFAOYSA-N
InChI=1S/C3H9N3S/c4-3(5)6-1-2-7/h7H,1-2H2,(H4,4,5,6)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
The 26th Congress of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Tromso, Norway, 13-17 June 2001.
2001 Aug
Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs.
2001 Aug
Role of nitric oxide in myocardial dysfunction after combined burn and smoke inhalation injury.
2001 Dec
Potentiation by aminoethylisothiourea of the extra-cellular Ca(2+) component of norepinephrine-induced contraction in rat femoral arteries.
2001 Jan 1
Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury.
2001 Mar
Effect of mercaptoethylguanidine scavengers of peroxynitrite on the development of experimental allergic encephalomyelitis in PLSJL mice.
2001 Sep 28
Human gingival fibroblasts produce nitric oxide in response to proinflammatory cytokines.
2002 Apr
Role of nitric oxide and reactive oxygen species in platelet-activating factor-induced microvascular leakage.
2002 May-Jun
Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats.
2004 Jun 16
New 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidinium alkaloids (phloeodictynes) from the New Caledonian shallow-water haplosclerid sponge Oceanapia fistulosa. Structural elucidation from mainly LC-tandem-MS-soft-ionization techniques and discovery of antiplasmodial activity.
2004 Mar 7
Nitric oxide is synthesized in acute leukemia cells after exposure to phenolic antioxidants and initially protects against mitochondrial membrane depolarization.
2004 Nov 8
Effect of exposure to cigarette smoke on carotid artery intimal thickening: the role of inducible NO synthase.
2004 Sep
Mercaptoethylguanidine inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expressions induced in rats after fluid-percussion brain injury.
2005 Aug
Protein 3-nitrotyrosine formation during Trypanosoma cruzi infection in mice.
2005 Dec
Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury.
2005 Jun 14
Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice.
2005 Jun 29
Inhibition of experimental gingivitis in beagle dogs with topical mercaptoalkylguanidines.
2006 Mar
Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.
2006 Mar 31
Coupling of TiO(2)-mediated enrichment and on-bead guanidinoethanethiol labeling for effective phosphopeptide analysis by matrix-assisted laser desorption/ionization mass spectrometry.
2007
Celastrus aculeatus Merr. suppresses the induction and progression of autoimmune arthritis by modulating immune response to heat-shock protein 65.
2007
Arginine-mimic labeling with guanidinoethanethiol to increase mass sensitivity of lysine-terminated phosphopeptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
2007
Protein phosphorylation analysis by site-specific arginine-mimic labeling in gel electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
2007 Nov 1
Postimmunization with IFN-gamma-secreting glioma cells combined with the inducible nitric oxide synthase inhibitor mercaptoethylguanidine prolongs survival of rats with intracerebral tumors.
2007 Sep 15
T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis.
2008
Scavenging of peroxynitrite reduces renal ischemia/reperfusion injury.
2008
Oxidative stress and anxiety: relationship and cellular pathways.
2009 Apr-Jun
Estimation of nitric oxide as an inflammatory marker in periodontitis.
2009 May
WY-14643, a Potent Peroxisome Proliferator Activator Receptor-α PPAR-α Agonist Ameliorates the Inflammatory Process Associated to Experimental Periodontitis.
2010
Effect of venlafaxine on bone loss associated with ligature-induced periodontitis in Wistar rats.
2010 Jun 14
Name Type Language
2-MERCAPTOETHYLGUANIDINE
Systematic Name English
GUANIDINE, N-(2-MERCAPTOETHYL)-
Systematic Name English
MEG
Common Name English
Code System Code Type Description
CAS
1190-74-5
Created by admin on Fri Dec 15 19:39:30 GMT 2023 , Edited by admin on Fri Dec 15 19:39:30 GMT 2023
PRIMARY
EPA CompTox
DTXSID00152290
Created by admin on Fri Dec 15 19:39:30 GMT 2023 , Edited by admin on Fri Dec 15 19:39:30 GMT 2023
PRIMARY
FDA UNII
S33ZNG2R5Y
Created by admin on Fri Dec 15 19:39:30 GMT 2023 , Edited by admin on Fri Dec 15 19:39:30 GMT 2023
PRIMARY
PUBCHEM
4070
Created by admin on Fri Dec 15 19:39:30 GMT 2023 , Edited by admin on Fri Dec 15 19:39:30 GMT 2023
PRIMARY