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Details

Stereochemistry ACHIRAL
Molecular Formula C3H9N3S
Molecular Weight 119.189
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-MERCAPTOETHYLGUANIDINE

SMILES

NC(=N)NCCS

InChI

InChIKey=GAPFINWZKMCSBG-UHFFFAOYSA-N
InChI=1S/C3H9N3S/c4-3(5)6-1-2-7/h7H,1-2H2,(H4,4,5,6)

HIDE SMILES / InChI

Molecular Formula C3H9N3S
Molecular Weight 119.189
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of venlafaxine on bone loss associated with ligature-induced periodontitis in Wistar rats.
2010-06-14
WY-14643, a Potent Peroxisome Proliferator Activator Receptor-α PPAR-α Agonist Ameliorates the Inflammatory Process Associated to Experimental Periodontitis.
2010
Estimation of nitric oxide as an inflammatory marker in periodontitis.
2009-05
Oxidative stress and anxiety: relationship and cellular pathways.
2009-01-16
T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis.
2008
Scavenging of peroxynitrite reduces renal ischemia/reperfusion injury.
2008
Protein phosphorylation analysis by site-specific arginine-mimic labeling in gel electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
2007-11-01
Postimmunization with IFN-gamma-secreting glioma cells combined with the inducible nitric oxide synthase inhibitor mercaptoethylguanidine prolongs survival of rats with intracerebral tumors.
2007-09-15
Coupling of TiO(2)-mediated enrichment and on-bead guanidinoethanethiol labeling for effective phosphopeptide analysis by matrix-assisted laser desorption/ionization mass spectrometry.
2007
Celastrus aculeatus Merr. suppresses the induction and progression of autoimmune arthritis by modulating immune response to heat-shock protein 65.
2007
Arginine-mimic labeling with guanidinoethanethiol to increase mass sensitivity of lysine-terminated phosphopeptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
2007
Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.
2006-03-31
Inhibition of experimental gingivitis in beagle dogs with topical mercaptoalkylguanidines.
2006-03
Protein 3-nitrotyrosine formation during Trypanosoma cruzi infection in mice.
2005-12
Mercaptoethylguanidine inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expressions induced in rats after fluid-percussion brain injury.
2005-08
Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice.
2005-06-29
Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury.
2005-06-14
Nitric oxide is synthesized in acute leukemia cells after exposure to phenolic antioxidants and initially protects against mitochondrial membrane depolarization.
2004-11-08
Effect of exposure to cigarette smoke on carotid artery intimal thickening: the role of inducible NO synthase.
2004-09
Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats.
2004-06-16
New 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidinium alkaloids (phloeodictynes) from the New Caledonian shallow-water haplosclerid sponge Oceanapia fistulosa. Structural elucidation from mainly LC-tandem-MS-soft-ionization techniques and discovery of antiplasmodial activity.
2004-03-07
Role of nitric oxide and reactive oxygen species in platelet-activating factor-induced microvascular leakage.
2002-07-05
Human gingival fibroblasts produce nitric oxide in response to proinflammatory cytokines.
2002-04
Role of nitric oxide in myocardial dysfunction after combined burn and smoke inhalation injury.
2001-12
Effect of mercaptoethylguanidine scavengers of peroxynitrite on the development of experimental allergic encephalomyelitis in PLSJL mice.
2001-09-28
The 26th Congress of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine, Tromso, Norway, 13-17 June 2001.
2001-08
Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs.
2001-08
Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury.
2001-03
Potentiation by aminoethylisothiourea of the extra-cellular Ca(2+) component of norepinephrine-induced contraction in rat femoral arteries.
2001-01-01
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:52:28 GMT 2025
Edited
by admin
on Mon Mar 31 19:52:28 GMT 2025
Record UNII
S33ZNG2R5Y
Record Status Validated (UNII)
Record Version
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Name Type Language
2-MERCAPTOETHYLGUANIDINE
Systematic Name English
MEG
Preferred Name English
GUANIDINE, N-(2-MERCAPTOETHYL)-
Systematic Name English
Code System Code Type Description
CAS
1190-74-5
Created by admin on Mon Mar 31 19:52:28 GMT 2025 , Edited by admin on Mon Mar 31 19:52:28 GMT 2025
PRIMARY
EPA CompTox
DTXSID00152290
Created by admin on Mon Mar 31 19:52:28 GMT 2025 , Edited by admin on Mon Mar 31 19:52:28 GMT 2025
PRIMARY
FDA UNII
S33ZNG2R5Y
Created by admin on Mon Mar 31 19:52:28 GMT 2025 , Edited by admin on Mon Mar 31 19:52:28 GMT 2025
PRIMARY
PUBCHEM
4070
Created by admin on Mon Mar 31 19:52:28 GMT 2025 , Edited by admin on Mon Mar 31 19:52:28 GMT 2025
PRIMARY