Details
| Stereochemistry | EPIMERIC |
| Molecular Formula | C19H22O2.C7H17NO5 |
| Molecular Weight | 477.5904 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CC(C(O)=O)C1=CC=C(C2CCCCC2)C3=C1C=CC=C3
InChI
InChIKey=SGAJMCQBAWHKKC-WZTVWXICSA-N
InChI=1S/C19H22O2.C7H17NO5/c1-13(19(20)21)15-11-12-16(14-7-3-2-4-8-14)18-10-6-5-9-17(15)18;1-8-2-4(10)6(12)7(13)5(11)3-9/h5-6,9-14H,2-4,7-8H2,1H3,(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: O19183 Gene ID: 791253.0 Gene Symbol: PTGS2 Target Organism: Equus caballus (Horse) |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | QUADRISOL Approved UseReduction of inflammation and relief of pain associated with musculo-skeletal disorders and soft tissue lesions (traumatic injuries and surgical trauma). Launch Date1997 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Comparison of vedaprofen and meloxicam in dogs with musculoskeletal pain and inflammation. | 2002 May |
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| The pharmacokinetics of vedaprofen and its enantiomers in dogs after single and multiple dosing. | 2005 Jun |
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| Influence of vedaprofen (Quadrisol) on quality and freezability of stallion semen. | 2005 Nov |
|
| Vedaprofen therapy in cats with upper respiratory tract infection or following ovariohysterectomy. | 2007 Feb |
|
| Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs. | 2008 Feb |
|
| Analgesic efficacy of perioperative use of vedaprofen, tramadol or their combination in cats undergoing ovariohysterectomy. | 2009 Jun |
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| Perioperative administration of vedaprofen, tramadol or their combination does not interfere with platelet aggregation, bleeding time and biochemical variables in cats. | 2009 Jun |
|
| Treatment of persistent mating-induced endometritis in mares with the non-steroid anti-inflammatory drug vedaprofen. | 2010 Dec |
|
| Practical experience with the treatment of recipient mares with a non-steroidal anti-inflammatory drug in an equine embryo transfer programme. | 2010 Dec |
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300000023674
Created by
admin on Fri Dec 15 16:59:23 GMT 2023 , Edited by admin on Fri Dec 15 16:59:23 GMT 2023
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S154JX9N3H
Created by
admin on Fri Dec 15 16:59:23 GMT 2023 , Edited by admin on Fri Dec 15 16:59:23 GMT 2023
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139033180
Created by
admin on Fri Dec 15 16:59:23 GMT 2023 , Edited by admin on Fri Dec 15 16:59:23 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD
