U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H3NS
Molecular Weight 73.117
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of METHYL ISOTHIOCYANATE

SMILES

CN=C=S

InChI

InChIKey=LGDSHSYDSCRFAB-UHFFFAOYSA-N
InChI=1S/C2H3NS/c1-3-2-4/h1H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Human chemosensory perception of methyl isothiocyanate: chemesthesis and odor.
2010-11
Dose response assessment for effects of acute exposure to methyl isothiocyanate (MITC).
2010-11
Absolute kinetics and reaction efficiencies of hydroxyl-radical-induced degradation of methyl isothiocyanate (MITC) in different quality waters.
2010-09
Emergency responder health: what have we learned from past disasters?
2010-08
Complexes of Gilman reagents with C-S and C-N double bonds: sigma or pi bonding?
2010-07-21
Surface water seal application to minimize volatilization loss of methyl isothiocyanate from soil columns.
2010-06
Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity.
2010-04-15
Microbial aspects of accelerated degradation of metam sodium in soil.
2010-04
Testing of a new disinfectant process for poultry viruses.
2010-03
Excessive longitudinal FEV1 decline and risks to future health: a case-control study.
2009-12
Oxidative stress and sodium methyldithiocarbamate-induced modulation of the macrophage response to lipopolysaccharide in vivo.
2009-06
Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya.
2009-06
Synthesis, Antiinflammatory and HIV-1 Integrase Inhibitory Activities of 1,2-Bis[5-thiazolyl]ethane-1,2-dione Derivatives.
2009-05
Accelerated degradation of metam-sodium in soil and consequences for root-disease management.
2009-04
Combinations of soil fumigants for methyl-bromide replacement.
2009
Determination of methyl isothiocyanate in air downwind of fields treated with metam-sodium by subsurface drip irrigation.
2008-08-27
Fumigation of wheat using liquid ethyl formate plus methyl isothiocyanate in 50-tonne farm bins.
2008-04
Herbal compounds and toxins modulating TRP channels.
2008-03
ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.
2008-03
Method development study for APR cartridge evaluation in fire overhaul exposures.
2007-11
Emission, distribution and leaching of methyl isothiocyanate and chloropicrin under different surface containments.
2007-06
Distribution and efficacy of drip-applied metam-sodium against the survival of Rhizoctonia solani and yellow nutsedge in plastic-mulched sandy soil beds.
2007-05
Methyl isothiocyanate residential community air assessment for South Franklin County, Washington.
2007-01
Optimization of metam sodium application by rotary spading injection.
2007
Combinations of reduced rates of 1,3-dichloropropene and dazomet as a broad spectrum soil fumigation strategy in view of methyl bromide replacement.
2007
Dithiocarbamates have a common toxic effect on zebrafish body axis formation.
2006-10-01
Effects of application methods of metam sodium and plastic covers on horizontal and vertical distributions of methyl isothiocyanate in bedded field plots.
2006-08
The enantioseparation of amino acids on a teicoplanin chiral stationary phase using non-aqueous mobile phases after pre-column derivatization with sulfur-containing reagents: the considerations of mobile phase composition and analyte structure variation on resolution enhancement.
2006-08
Evaluation of volatile low molecular weight insecticides using Drosophila melanogaster as a model.
2006-07
Involvement of three mechanisms in the alteration of cytokine responses by sodium methyldithiocarbamate.
2006-06-01
Modeling methyl isothiocyanate soil flux and emission ratio from a field following a chemigation of metam-sodium.
2006-04-06
Fumigant distribution in forest nursery soils under water seal and plastic film after application of dazomet, metam-sodium and chloropicrin.
2006-03
Physical, chemical and environmental properties of selected chemical alternatives for the pre-plant use of methyl bromide as soil fumigant.
2006-02
Ab initio computational insight into the ion-pair S(N)2 reaction of lithium isothiocyanate and methyl fluoride in the gas phase and in acetone solution.
2006-01
Biofumigation: environmental impacts on the biological activity of diverse pure and plant-derived isothiocyanates.
2005-11
The crucial role of calcium interacting with soil pH in enhanced biodegradation of metam-sodium.
2005-09
Sodium methyldithiocarbamate inhibits MAP kinase activation through toll-like receptor 4, alters cytokine production by mouse peritoneal macrophages, and suppresses innate immunity.
2005-09
Degradation of methyl isothiocyanate and chloropicrin in forest nursery soils.
2005-08-11
The factors that influence the elution order for the resolution of amino acids on vancomycin phase using the polar-organic mobile phases after their pre-column derivatization with electrophilic reagents.
2005-07
Application of solid phase microextraction for the determination of soil fumigants in water and soil samples.
2005-01
Illnesses related to shank application of metam-sodium, Arvin, California, July 2002.
2005
Effect of combined application of methyl isothiocyanate and chloropicrin on their transformation.
2004-11-13
Effect of application variables on emissions and distribution of fumigants applied via subsurface drip irrigation.
2004-11-01
Developmental toxicity of the dithiocarbamate pesticide sodium metam in zebrafish.
2004-10
Modeling of methyl isothiocyanate air concentrations associated with community illnesses following a metam-sodium sprinkler application.
2004-07
[Determination of isothiocyanates in human urine by high performance liquid chromatography].
2004-01
Leaching potential of persistent soil fumigant residues.
2003-11-15
Characterizing the influence of structure and route of exposure on the disposition of dithiocarbamates using toluene-3,4-dithiol analysis of blood and urinary carbon disulfide metabolites.
2003-11
[Synthesis and nNOS inhibitory activity of benzenealkyl isothiourea compounds].
2003-08
Status of chemical alternatives to methyl bromide for pre-plant fumigation of soil.
2002-12
Patents
Name Type Language
METHYL ISOTHIOCYANATE
FHFI   HSDB   ISO   MI  
Systematic Name English
ISOTHIOCYANATOMETHANE
Preferred Name English
METHYL ISOTHIOCYANATE [HSDB]
Common Name English
METHANE, ISOTHIOCYANATO-
Systematic Name English
METHYL ISOTHIOCYANATE [FHFI]
Common Name English
FEMA NO. 4426
Code English
MITC
Common Name English
METHYL ISOTHIOCYANATE [ISO]
Common Name English
METHYL ISOTHIOCYANATE [MI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 68103
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
Code System Code Type Description
MESH
C005227
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
EPA CompTox
DTXSID2027204
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
ALANWOOD
methyl isothiocyanate
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
WIKIPEDIA
METHYL ISOTHIOCYANATE
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
MERCK INDEX
m7434
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY Merck Index
ECHA (EC/EINECS)
209-132-5
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
HSDB
6396
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
CHEBI
78337
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
PUBCHEM
11167
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
FDA UNII
RWE2M5YDW1
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
JECFA MONOGRAPH
1862
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY
CAS
556-61-6
Created by admin on Mon Mar 31 19:34:12 GMT 2025 , Edited by admin on Mon Mar 31 19:34:12 GMT 2025
PRIMARY