1-ETHYL-3-(3-(DIMETHYLAMINO)PROPYL)CARBODIIMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H17N3
Molecular Weight	155.2407
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure of 1-ETHYL-3-(3-(DIMETHYLAMINO)PROPYL)CARBODIIMIDE

SMILES

CCN=C=NCCCN(C)C

InChI

InChIKey=LMDZBCPBFSXMTL-UHFFFAOYSA-N

InChI=1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

HIDE SMILES / InChI

Description

1-Ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC) is a water-soluble carbodiimide. EDC is commonly used for the peptide synthesis, protein crosslinking to nucleic acids, preparation of immunoconjugates. EDC is also used in combination with N-hydroxysuccinimide (NHS) for the immobilisation of large biomolecules.

Approval Year

PubMed

Show entries

Title	Date	PubMed
Cross-linking by 1-ethyl-3- (3-dimethylaminopropyl)-carbodiimide (EDC) of a collagen/elastin membrane meant to be used as a dermal substitute: effects on physical, biochemical and biological features in vitro.	2001 May	15348284
The influence of crosslinking agents and diamines on the pore size, morphology and the biological stability of collagen sponges and their effect on cell penetration through the sponge matrix.	2001 Sep	15348233
Cytotoxicity evaluation of gelatin sponges prepared with different cross-linking agents.	2002	12518800
Further stabilization of earthworm serine protease by chemical modification and immobilization.	2002 Dec	12596880
Polymerized degradable hyaluronan--a platform for stent coating with inherent inhibitory effects on neointimal formation in a porcine coronary model.	2002 Dec	12518961

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Patents

Sample Use Guides

In Vitro Use Guide

Close to 13 mol of EDC per mol of ECF1 was incorporated into the enzyme at 95% inhibition of ATPase activity. Two-thirds of the label was found to be associated with subunit beta with a stoichiometry of about 3 mol of EDC per mol of beta.

Show entries

Name

Type

Language

1-ETHYL-3-(3-(DIMETHYLAMINO)PROPYL)CARBODIIMIDE

Systematic Name

English

EDAC

Common Name

English

N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE

Systematic Name

English

N3-(ETHYLCARBONIMIDOYL)-N1,N1-DIMETHYL-1,3-PROPANEDIAMINE

Systematic Name

English

1-ETHYL-3-(DIMETHYLAMINOPROPYL)CARBODIIMIDE

Systematic Name

English

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Code System

Code

Type

Description

ECHA (EC/EINECS)

217-579-2

PRIMARY

CAS

1892-57-5

PRIMARY

PUBCHEM

15908

PRIMARY

EPA CompTox

DTXSID60865258

PRIMARY

FDA UNII

RJ5OZG6I4A

PRIMARY

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SUBSTANCE RECORD


					RJ5OZG6I4A

1-ETHYL-3-(3-(DIMETHYLAMINO)PROPYL)CARBODIIMIDE