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Details

Stereochemistry ACHIRAL
Molecular Formula C14H9F9N2O
Molecular Weight 392.2197
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LGD-2226

SMILES

FC(F)(F)CN(CC(F)(F)F)C1=CC2=C(NC(=O)C=C2C(F)(F)F)C=C1

InChI

InChIKey=ULBPQWIGZUGPHU-UHFFFAOYSA-N
InChI=1S/C14H9F9N2O/c15-12(16,17)5-25(6-13(18,19)20)7-1-2-10-8(3-7)9(14(21,22)23)4-11(26)24-10/h1-4H,5-6H2,(H,24,26)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226.
2006 Nov 1
An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate.
2007 Jan
Selective androgen receptor modulators in preclinical and clinical development.
2008
Cell-specific activation of the human skeletal alpha-actin by androgens.
2008 Mar
Patents

Patents

Name Type Language
LGD-2226
Common Name English
6-(BIS-(2,2,2-TRIFLUOROETHYL)AMINO)-4-TRIFLUOROMETHYL-1H-QUINOLIN-2-ONE
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-LGD-2226
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
Code System Code Type Description
WIKIPEDIA
LGD-2226
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
FDA UNII
RI376RM5MT
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
EPA CompTox
DTXSID10186546
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
DRUG BANK
DB08089
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
PUBCHEM
11560224
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
CAS
328947-93-9
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY