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Details

Stereochemistry ACHIRAL
Molecular Formula C14H9F9N2O
Molecular Weight 392.2197
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LGD-2226

SMILES

FC(F)(F)CN(CC(F)(F)F)C1=CC2=C(NC(=O)C=C2C(F)(F)F)C=C1

InChI

InChIKey=ULBPQWIGZUGPHU-UHFFFAOYSA-N
InChI=1S/C14H9F9N2O/c15-12(16,17)5-25(6-13(18,19)20)7-1-2-10-8(3-7)9(14(21,22)23)4-11(26)24-10/h1-4H,5-6H2,(H,24,26)

HIDE SMILES / InChI

Molecular Formula C14H9F9N2O
Molecular Weight 392.2197
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Discovery of 6-N,N-bis(2,2,2-trifluoroethyl)amino- 4-trifluoromethylquinolin-2(1H)-one as a novel selective androgen receptor modulator.
2006 Oct 19
An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate.
2007 Jan
Cell-specific activation of the human skeletal alpha-actin by androgens.
2008 Mar
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 19:41:17 GMT 2023
Edited
by admin
on Fri Dec 15 19:41:17 GMT 2023
Record UNII
RI376RM5MT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LGD-2226
Common Name English
6-(BIS-(2,2,2-TRIFLUOROETHYL)AMINO)-4-TRIFLUOROMETHYL-1H-QUINOLIN-2-ONE
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-LGD-2226
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
Code System Code Type Description
WIKIPEDIA
LGD-2226
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
FDA UNII
RI376RM5MT
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
EPA CompTox
DTXSID10186546
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
DRUG BANK
DB08089
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
PUBCHEM
11560224
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY
CAS
328947-93-9
Created by admin on Fri Dec 15 19:41:17 GMT 2023 , Edited by admin on Fri Dec 15 19:41:17 GMT 2023
PRIMARY