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Details

Stereochemistry ACHIRAL
Molecular Formula C8H12N4O3S
Molecular Weight 244.271
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CARNIDAZOLE

SMILES

COC(=S)NCCN1C(C)=NC=C1[N+]([O-])=O

InChI

InChIKey=OVEVHVURWWTPFC-UHFFFAOYSA-N
InChI=1S/C8H12N4O3S/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2/h5H,3-4H2,1-2H3,(H,9,16)

HIDE SMILES / InChI

Description

Carnidazole (trade name Spartrix) is an antiprotozoal drug of the nitroimidazole class used in veterinary medicine. Spartrix (Carnidazole) is indicated for oral treatment of trichomoniasis (canker) in ornamental and homing (non-food) pigeons.

Originator

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Spartrix
Primary
PubMed

PubMed

TitleDatePubMed
Antiprotozoals effective in vitro against the scuticociliate fish pathogen Philasterides dicentrarchi.
2002 Jun 3
Crystal structure of carnidazole form II from synchrotron X-ray powder diffraction: structural comparison with form I, the hydrated form and the low energy conformations in vacuo.
2006 Oct
Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry.
2009 May 15
Rapid confirmatory method for the determination of 11 nitroimidazoles in egg using liquid chromatography tandem mass spectrometry.
2009 Nov 13
Rapid multi-class multi-residue method for the confirmation of chloramphenicol and eleven nitroimidazoles in milk and honey by liquid chromatography-tandem mass spectrometry (LC-MS).
2010 Sep
Patents

Sample Use Guides

In Vivo Use Guide
Pigeons: 1 tablet per adult pigeon and half tablet per young pigeon. A single dose is usually sufficient. In cases where pigeon does not respond within 3 days, it may be treated again.
Route of Administration: Oral
In Vitro Use Guide
Carnidazole, dimetridazole, metronidazole and ornidazole showed a similar activity against isolates HF26, 79P and P2, with MLCs ranging from 1.9 to 7.8 ug/ml.
Name Type Language
CARNIDAZOLE
GREEN BOOK   INN   MART.   MI   USAN  
INN   USAN  
Official Name English
R 28,096 FREE BASE
Code English
CARNIDAZOLE [MART.]
Common Name English
R-25831
Code English
R 25,831
Code English
NSC-293873
Code English
CARBAMOTHIOIC ACID, (2-(2-METHYL-5-NITRO-1H-IMIDAZOL-1-YL)ETHYL)-, O-METHYL ESTER
Common Name English
R-28096 FREE BASE
Code English
CARNIDAZOLE [GREEN BOOK]
Common Name English
CARNIDAZOLE [INN]
Common Name English
CARNIDAZOLE [MI]
Common Name English
CARNIDAZOLE [USAN]
Common Name English
O-METHYL (2-(2-METHYL-5-NITROIMIDAZOL-1-YL)ETHYL)THIOCARBAMATE
Systematic Name English
Classification Tree Code System Code
CFR 21 CFR 520.302
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
WHO-VATC QP51AA09
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
Code System Code Type Description
ECHA (EC/EINECS)
255-663-0
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
MERCK INDEX
M3118
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY Merck Index
MESH
C014394
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
EVMPD
SUB06133MIG
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
PUBCHEM
3032998
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
CAS
42116-76-7
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
NCI_THESAURUS
C78095
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
WIKIPEDIA
Carnidazole
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
EPA CompTox
42116-76-7
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
INN
3625
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY
ChEMBL
CHEMBL135000
Created by admin on Tue Oct 22 13:32:23 UTC 2019 , Edited by admin on Tue Oct 22 13:32:23 UTC 2019
PRIMARY