Details
Stereochemistry | ACHIRAL |
Molecular Formula | C8H12N4O3S.ClH |
Molecular Weight | 280.732 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.COC(=S)NCCN1C(C)=NC=C1[N+]([O-])=O
InChI
InChIKey=RIUCUZVIVKJIFC-UHFFFAOYSA-N
InChI=1S/C8H12N4O3S.ClH/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2;/h5H,3-4H2,1-2H3,(H,9,16);1H
Molecular Formula | C8H12N4O3S |
Molecular Weight | 244.271 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionSources: https://www.drugs.com/international/carnidazole.html
Sources: https://www.drugs.com/international/carnidazole.html
Carnidazole (trade name Spartrix) is an antiprotozoal drug of the nitroimidazole class used in veterinary medicine. Spartrix (Carnidazole) is indicated for oral treatment of trichomoniasis (canker) in ornamental and homing (non-food) pigeons.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL613161 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9786623 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Curative | Unknown Approved UseUnknown |
|||
Curative | Spartrix Approved UseSpartrix (Carnidazole) is indicated for oral treatment of trichomoniasis (canker) in ornamental and homing (non-food) pigeons. Launch Date1989 |
PubMed
Title | Date | PubMed |
---|---|---|
Antiprotozoals effective in vitro against the scuticociliate fish pathogen Philasterides dicentrarchi. | 2002 Jun 3 |
|
Crystal structure of carnidazole form II from synchrotron X-ray powder diffraction: structural comparison with form I, the hydrated form and the low energy conformations in vacuo. | 2006 Oct |
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Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry. | 2009 May 15 |
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Rapid confirmatory method for the determination of 11 nitroimidazoles in egg using liquid chromatography tandem mass spectrometry. | 2009 Nov 13 |
|
Rapid multi-class multi-residue method for the confirmation of chloramphenicol and eleven nitroimidazoles in milk and honey by liquid chromatography-tandem mass spectrometry (LC-MS). | 2010 Sep |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: http://www.jedds.com/shop/spartrix-tablets-50-count/
Pigeons: 1 tablet per adult pigeon and half tablet per young pigeon. A single dose is usually sufficient. In cases where pigeon does not respond within 3 days, it may be treated again.
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9786623
Carnidazole, dimetridazole, metronidazole and ornidazole showed a similar activity against isolates HF26, 79P and P2, with MLCs ranging from 1.9 to 7.8 ug/ml.
Substance Class |
Chemical
Created
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Edited
Sat Dec 16 12:44:19 GMT 2023
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Record UNII |
G0I5C2CC38
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Record Status |
Validated (UNII)
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Record Version |
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