ISOMOLPAN HYDROCHLORIDE

Cl.[H][C@@]12COC3=C(C=C(O)C=C3)[C@@]1([H])CCCN2CCC

InChIKey=JFSZKRWNAVLJHH-QMDUSEKHSA-N

InChI=1S/C15H21NO2.ClH/c1-2-7-16-8-3-4-12-13-9-11(17)5-6-15(13)18-10-14(12)16;/h5-6,9,12,14,17H,2-4,7-8,10H2,1H3;1H/t12-,14-;/m1./s1

ISOMOLPAN is a selective D3/D2 receptor agonist.

PubMed

Title	Date	PubMed
Modulation of in vivo dopamine release by D2 but not D1 receptor agonists and antagonists.	1987 Mar	2949060
Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways.	1995 Nov	7473181
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.	1998 May	9539213
Discriminative stimulus properties of the dopamine D3 receptor agonists, PD128,907 and 7-OH-DPAT: a comparative characterization with novel ligands at D3 versus D2 receptors.	2000 Feb 14	10728880

Patents

Name

Type

Language

ISOMOLPAN HYDROCHLORIDE

Official Name

English

Isomolpan hydrochloride [WHO-DD]

Common Name

English

CGS 15855A

Code

English

CGS-15855A

Code

English

(±)-TRANS-1,3,4,4A,5,10B-HEXAHYDRO-4-PROPYL-2H-(1)BENZOPYRANO(3,4-B)PYRIDIN-9-OL HYDROCHLORIDE

Common Name

English

ISOMOLPAN HYDROCHLORIDE [USAN]

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2220428