Details
Stereochemistry | EPIMERIC |
Molecular Formula | C21H31NO2.ClH |
Molecular Weight | 365.937 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 3 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CCN(CC)CCCOC(=O)C1(C[C@@H]2CC[C@H]1C2)C3=CC=CC=C3
InChI
InChIKey=ODVPRPWQGNOPAY-PWITVKHSSA-N
InChI=1S/C21H31NO2.ClH/c1-3-22(4-2)13-8-14-24-20(23)21(18-9-6-5-7-10-18)16-17-11-12-19(21)15-17;/h5-7,9-10,17,19H,3-4,8,11-16H2,1-2H3;1H/t17-,19+,21?;/m1./s1
Bornaptine is a synthetic anticholinergic drug. The compound is a nonselective M1 and M4 antagonist and was shown to inhibit the negative inotropic response to carbachol in the isolated left atrium of the rat with pA2 of 7.27. Bornaprine is used for the treatment of symptoms of Parkinson's disease. A clinical trial showed the superiority of Bornaprine over placebo in reducing parkinsonian tremor. Bornaptine demonstrated positive results in localized hyperhidrosis.
Approval Year
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DTXSID70949699
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248-100-5
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235767
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118984396
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26908-91-8
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100000091913
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C006088
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R99RGW1B2Q
Created by
admin on Fri Dec 15 17:03:26 GMT 2023 , Edited by admin on Fri Dec 15 17:03:26 GMT 2023
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SUB00856MIG
Created by
admin on Fri Dec 15 17:03:26 GMT 2023 , Edited by admin on Fri Dec 15 17:03:26 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD