Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C28H41N3O3 |
| Molecular Weight | 467.6434 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCN(CCC)C(=O)C(CC1=CC=C(OCCN(CC)CC)C=C1)NC(=O)C2=CC=CC=C2
InChI
InChIKey=FDBWMYOFXWMGEY-UHFFFAOYSA-N
InChI=1S/C28H41N3O3/c1-5-18-31(19-6-2)28(33)26(29-27(32)24-12-10-9-11-13-24)22-23-14-16-25(17-15-23)34-21-20-30(7-3)8-4/h9-17,26H,5-8,18-22H2,1-4H3,(H,29,32)
Tiropramide is an antispasmodic medication. It acts by increasing cAMP concentration in smooth muscle possibly because of inhibition of cAMP catabolism. The drug is marketed worldwide for the treatment of irritable bowel syndrome, biliary dyskinesia, acute spasmodic dysphoric syndromes, and other urological and gynecological disorders.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: GO:0006939 |
19.0 µM [IC50] |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | ALFOSPAS Approved UsePainful-spastic syndromes such as acute hepatobiliary colic, abdominal different nature, kidney or ureteral. Spasms and abdominal pain originating from gastrointestinal dyskinesia, cholelithiasis, cholecystitis, post-surgical adhesions. |
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WHO-VATC |
QA03AC05
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WHO-ATC |
A03AC05
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NCI_THESAURUS |
C29698
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m10892
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SUB11119MIG
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2681
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C152660
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55837-29-1
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38315
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DB13091
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CHEMBL2104688
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TIROPRAMIDE
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C031173
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42262
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)
