URIDINE PHOSPHATE DIPOTASSIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H12N2O12P2.2K
Molecular Weight	480.3419
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of URIDINE PHOSPHATE DIPOTASSIUM

Structure Search

SMILES

[K+].[K+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O

InChI

InChIKey=QLYHPAJMTFPEHP-WFIJOQBCSA-L

InChI=1S/C9H14N2O12P2.2K/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
CDP-choline pathway 3 Target ID: GO:0006657 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16126180	Activator 1447

PubMed

Title	Date	PubMed
Evaluation of reference genes for quantitative reverse-transcription polymerase chain reaction normalization in infected tomato plants.	2010-11	21029324
Mutational analysis of the C-terminal FATC domain of Saccharomyces cerevisiae Tra1.	2010-10	20635087
Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.	2010-08-24	20808768
The impact of mRNA structure on guide RNA targeting in kinetoplastid RNA editing.	2010-08-17	20808932
3'-coterminal subgenomic RNAs and putative cis-acting elements of Grapevine leafroll-associated virus 3 reveals 'unique' features of gene expression strategy in the genus Ampelovirus.	2010-08-03	20682046
RNA virus replication complexes.	2010-07-22	20661480
Comparison of koala LPCoLN and human strains of Chlamydia pneumoniae highlights extended genetic diversity in the species.	2010-07-21	20646324
The macroscopic rate of nucleic acid translocation by hepatitis C virus helicase NS3h is dependent on both sugar and base moieties.	2010-07-16	20451531
Identifying essential genes in bacterial metabolic networks with machine learning methods.	2010-05-03	20438628
Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis.	2010-04-19	20403182
The Alveolate Perkinsus marinus: biological insights from EST gene discovery.	2010-04-07	20374649
The 3'-terminal sequence of Bamboo mosaic virus minus-strand RNA interacts with RNA-dependent RNA polymerase and initiates plus-strand RNA synthesis.	2010-03	20447270
Flavin-dependent thymidylate synthase: a novel pathway towards thymine.	2010-01-01	19643076
Improving the quality of infant sleep through the inclusion at supper of cereals enriched with tryptophan, adenosine-5'-phosphate, and uridine-5'-phosphate.	2009-12	19925721
The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.	2009-09-10	20157568
TbPIF5 is a Trypanosoma brucei mitochondrial DNA helicase involved in processing of minicircle Okazaki fragments.	2009-09	19779567
Post-transcriptional regulation of gene expression in plants during abiotic stress.	2009-07-10	19742130
The complex regulation of HIC (Human I-mfa domain containing protein) expression.	2009-07-07	19582149
Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH).	2009-07-01	19570206
Expression and subcellular localization of kinetoplast-associated proteins in the different developmental stages of Trypanosoma cruzi.	2009-06-04	19497120
Toward understanding the conformational dynamics of RNA ligation.	2009-02-03	19133737
Unique GTP-binding pocket and allostery of uridylate kinase from a gram-negative phytopathogenic bacterium.	2009-01-30	19059268
The crystal structure of UMP kinase from Bacillus anthracis (BA1797) reveals an allosteric nucleotide-binding site.	2008-09-19	18625239
Dietary intake of selected B vitamins in relation to risk of major cancers in women.	2008-09-02	18665162
Comparative phylogenomics and multi-gene cluster analyses of the Citrus Huanglongbing (HLB)-associated bacterium Candidatus Liberibacter.	2008-08-28	18755041
Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein.	2008-06	18547518
Trypanosoma brucei RNA editing protein TbMP42 (band VI) is crucial for the endonucleolytic cleavages but not the subsequent steps of U-deletion and U-insertion.	2008-06	18441050
The binary protein interactome of Treponema pallidum--the syphilis spirochete.	2008-05-28	18509523
Complete sequence and analysis of the mitochondrial genome of Hemiselmis andersenii CCMP644 (Cryptophyceae).	2008-05-12	18474103
Identification of a bacterial-like HslVU protease in the mitochondria of Trypanosoma brucei and its role in mitochondrial DNA replication.	2008-04-18	18421378
Reversible sialylation: synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid from cytidine 5'-monophosphate with alpha2,3-sialyl O-glycan-, glycolipid-, and macromolecule-based donors yields diverse sialylated products.	2008-01-08	18067323
Turkey coronavirus non-structure protein NSP15--an endoribonuclease.	2008	19023218
Functional and structural insights revealed by molecular dynamics simulations of an essential RNA editing ligase in Trypanosoma brucei.	2007-11-14	18060084
Differences in glutamic acid and 5'-ribonucleotide contents between flesh and pulp of tomatoes and the relationship with umami taste.	2007-07-11	17567148
Expression of RNA virus proteins by RNA polymerase II dependent expression plasmids is hindered at multiple steps.	2007-06-05	17550613
Sendai virus RNA polymerase scanning for mRNA start sites at gene junctions.	2007-06-05	17300823
Identification of quorum sensing-related regulons in Vibrio vulnificus by two-dimensional gel electrophoresis and differentially displayed reverse transcriptase PCR.	2007-06	17506728
RNA-editing-associated protein 1 null mutant reveals link to mitochondrial RNA stability.	2007-06	17416633
The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates.	2007-04	17355283
Modulation of mRNA stability as a novel therapeutic approach.	2007-04	17320967
Structural and enzymatic investigation of the Sulfolobus solfataricus uridylate kinase shows competitive UTP inhibition and the lack of GTP stimulation.	2007-03-13	17297917
The RNA-binding protein HuD binds acetylcholinesterase mRNA in neurons and regulates its expression after axotomy.	2007-01-17	17234598
RNA-protein interactions in assembled editing complexes in trypanosomes.	2007	17662838
RNA recognition and cleavage by the SARS coronavirus endoribonuclease.	2006-08-11	16828802
Molecular dynamics DFT:B3LYP study of guanosinetriphosphate conversion into guanosinemonophosphate upon Mg2+ chelation of alpha and beta phosphate oxygens of the triphosphate tail.	2006-05-14	16751877
KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei.	2006-05	16601201
Design, synthesis and structural analysis of novel bent DNAs containing cyclic uridylate dimer analogues.	2006	17150818
Comparison between tryptophan methoxyindole and kynurenine metabolic pathways in normal and preterm neonates and in neonates with acute fetal distress.	1998-07	9703384
Antibody-nucleic acid complexes. Oligo(dG)n and -(dT)n specificities associated with anti-DNA antibodies from autoimmune MRL mice.	1989-12-26	2559771
Inhibition of herpes simplex virus DNA polymerase by purine ribonucleoside monophosphates.	1986-02-05	3003073

Patents

Name

Type

Language

URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE), DIPOTASSIUM SALT

Preferred Name

English

URIDINE PHOSPHATE DIPOTASSIUM

Systematic Name

English

Uridine phosphate dipotassium [WHO-DD]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID70243088