U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C16H13ClN2O.C2H3Cl3O2
Molecular Weight 450.143
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHLORAZEPAM

SMILES

OC(O)C(Cl)(Cl)Cl.CN1C2=CC=C(Cl)C=C2C(=NCC1=O)C3=CC=CC=C3

InChI

InChIKey=SDWAACKJISOIGZ-UHFFFAOYSA-N
InChI=1S/C16H13ClN2O.C2H3Cl3O2/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11;3-2(4,5)1(6)7/h2-9H,10H2,1H3;1,6-7H

HIDE SMILES / InChI

Approval Year

Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
10.4 ng/mL
2 mg single, oral
dose: 2 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
CHLORAZEPAM plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
242 ng × h/mL
2 mg single, oral
dose: 2 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
CHLORAZEPAM plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
26.4 h
2 mg single, oral
dose: 2 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
CHLORAZEPAM plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: FASTED
Name Type Language
CHLORAZEPAM
WHO-DD  
Common Name English
CLORAZEPAT
Brand Name English
1,1-ETHANEDIOL, 2,2,2-TRICHLORO-, COMPD. WITH 7-CHLORO-1,3-DIHYDRO-1-METHYL-5-PHENYL-2H-1,4-BENZODIAZEPIN-2-ONE (1:1)
Systematic Name English
2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1,3-DIHYDRO-1-METHYL-5-PHENYL-, COMPD. WITH 2,2,2-TRICHLORO-1,1-ETHANEDIOL (1:1)
Systematic Name English
Chlorazepam [WHO-DD]
Common Name English
CHLORAL HYDRATE-DIAZEPAM (1:1)
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
252-308-1
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
PRIMARY
CAS
37355-31-0
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
SUPERSEDED
EVMPD
SUB11919MIG
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
PRIMARY
CAS
34985-87-0
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
PRIMARY
PUBCHEM
3084599
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
PRIMARY
SMS_ID
300000039635
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
PRIMARY
FDA UNII
R14J9HX8JT
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
PRIMARY
EPA CompTox
DTXSID70188526
Created by admin on Sat Dec 16 09:59:22 GMT 2023 , Edited by admin on Sat Dec 16 09:59:22 GMT 2023
PRIMARY