NEOTETRAZOLIUM CHLORIDE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C38H28N8.2Cl
Molecular Weight	667.589
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cl-].[Cl-].C1=CC=C(C=C1)N2N=C(N=[N+]2C3=CC=C(C=C3)C4=CC=C(C=C4)[N+]5=NC(=NN5C6=CC=CC=C6)C7=CC=CC=C7)C8=CC=CC=C8

InChI

InChIKey=WYFYSTBFFDOVJW-UHFFFAOYSA-L

InChI=1S/C38H28N8.2ClH/c1-5-13-31(14-6-1)37-39-43(33-17-9-3-10-18-33)45(41-37)35-25-21-29(22-26-35)30-23-27-36(28-24-30)46-42-38(32-15-7-2-8-16-32)40-44(46)34-19-11-4-12-20-34;;/h1-28H;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5552733 | https://www.ncbi.nlm.nih.gov/pubmed/79413 | https://www.ncbi.nlm.nih.gov/pubmed/2477789

Neotetrazolium chloride is used for the histochemical detection of dehydrogenases. Neotetrazolium reduction can be used for discriminating malignant cells from nonmalignant cells. Neotetrazolium chloride is used for the colorimetric estimation of succinic dehydrogenase activity in a tumor sensitivity test to chemotherapeutic agents. Neotetrazolium chloride is also used in the microagglutination test and in the Neotetrazolium Test (NTC) for histologic evaluation of myocardial sections in acute necrobiosis of the myocardium.

Approval Year

PubMed

Title	Date	PubMed
Spectrophotometric method for the determination of carbidopa using neotetrazolium chloride.	1992-12	1361549
Oxygen and the production of formazan from neotetrazolium chloride.	1978-07-12	689923
Neotetrazolium staining of three avian Mycoplasma serotypes for microagglutination test.	1978-04-01	79413
The quantification of formazans in tissue sections by microdensitometry. I. The use of neotetrazolium chloride.	1976-07	60309
Spectrophotometric determination of dipyrone with neotetrazolium chloride.	1975-07	1147265

Name

Type

Language

NSC-27621

Preferred Name

English

NEOTETRAZOLIUM CHLORIDE

Common Name

English

2H-TETRAZOLIUM, 3,3'-(1,1'-BIPHENYL)-4,4'-DIYLBIS(2,5-DIPHENYL-, CHLORIDE (1:2)

Common Name

English

3,3'-(1,1'-BIPHENYL)-4,4'-DIYLBIS(2,5-DIPHENYL-2H-TETRAZOLIUM) DICHLORIDE

Common Name

English

NEOTETRAZOLIUM CHLORIDE [MI]

Common Name

English

3,3'-(4,4'-BIPHENYLENE)BIS(2,5-DIPHENYL-2H-TETRAZOLIUM) DICHLORIDE

Common Name

English

TP

Common Name

English

NEO-T

Common Name

English

NEOTETRAZOLIUM BLUE

Common Name

English

2,2',5,5'-TETRAPHENYL-3,3'-(P-DIPHENYLENE)DITETRAZOLIUM CHLORIDE

Common Name

English

NTC

Common Name

English

2,2'-(P-DIPHENYLENE)-BIS(3,5-DIPHENYL)DITETRAZOLIUM CHLORIDE

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID20889339