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Details

Stereochemistry ACHIRAL
Molecular Formula C38H28N8.2Cl
Molecular Weight 667.589
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NEOTETRAZOLIUM CHLORIDE

SMILES

[Cl-].[Cl-].C1=CC=C(C=C1)N2N=C(N=[N+]2C3=CC=C(C=C3)C4=CC=C(C=C4)[N+]5=NC(=NN5C6=CC=CC=C6)C7=CC=CC=C7)C8=CC=CC=C8

InChI

InChIKey=WYFYSTBFFDOVJW-UHFFFAOYSA-L
InChI=1S/C38H28N8.2ClH/c1-5-13-31(14-6-1)37-39-43(33-17-9-3-10-18-33)45(41-37)35-25-21-29(22-26-35)30-23-27-36(28-24-30)46-42-38(32-15-7-2-8-16-32)40-44(46)34-19-11-4-12-20-34;;/h1-28H;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Molecular Formula C38H28N8
Molecular Weight 596.6825
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Neotetrazolium chloride is used for the histochemical detection of dehydrogenases. Neotetrazolium reduction can be used for discriminating malignant cells from nonmalignant cells. Neotetrazolium chloride is used for the colorimetric estimation of succinic dehydrogenase activity in a tumor sensitivity test to chemotherapeutic agents. Neotetrazolium chloride is also used in the microagglutination test and in the Neotetrazolium Test (NTC) for histologic evaluation of myocardial sections in acute necrobiosis of the myocardium.

Approval Year

PubMed

PubMed

TitleDatePubMed
Spectrophotometric method for the determination of carbidopa using neotetrazolium chloride.
1992-12
Oxygen and the production of formazan from neotetrazolium chloride.
1978-07-12
Neotetrazolium staining of three avian Mycoplasma serotypes for microagglutination test.
1978-04-01
The quantification of formazans in tissue sections by microdensitometry. I. The use of neotetrazolium chloride.
1976-07
Spectrophotometric determination of dipyrone with neotetrazolium chloride.
1975-07
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:40:22 GMT 2025
Edited
by admin
on Mon Mar 31 20:40:22 GMT 2025
Record UNII
QL8L44VE6R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-27621
Preferred Name English
NEOTETRAZOLIUM CHLORIDE
MI  
Common Name English
2H-TETRAZOLIUM, 3,3'-(1,1'-BIPHENYL)-4,4'-DIYLBIS(2,5-DIPHENYL-, CHLORIDE (1:2)
Common Name English
3,3'-(1,1'-BIPHENYL)-4,4'-DIYLBIS(2,5-DIPHENYL-2H-TETRAZOLIUM) DICHLORIDE
Common Name English
NEOTETRAZOLIUM CHLORIDE [MI]
Common Name English
3,3'-(4,4'-BIPHENYLENE)BIS(2,5-DIPHENYL-2H-TETRAZOLIUM) DICHLORIDE
Common Name English
TP
Common Name English
NEO-T
Common Name English
NEOTETRAZOLIUM BLUE
Common Name English
2,2',5,5'-TETRAPHENYL-3,3'-(P-DIPHENYLENE)DITETRAZOLIUM CHLORIDE
Common Name English
NTC
Common Name English
2,2'-(P-DIPHENYLENE)-BIS(3,5-DIPHENYL)DITETRAZOLIUM CHLORIDE
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID20889339
Created by admin on Mon Mar 31 20:40:22 GMT 2025 , Edited by admin on Mon Mar 31 20:40:22 GMT 2025
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FDA UNII
QL8L44VE6R
Created by admin on Mon Mar 31 20:40:22 GMT 2025 , Edited by admin on Mon Mar 31 20:40:22 GMT 2025
PRIMARY
MERCK INDEX
m7821
Created by admin on Mon Mar 31 20:40:22 GMT 2025 , Edited by admin on Mon Mar 31 20:40:22 GMT 2025
PRIMARY Merck Index
CAS
298-95-3
Created by admin on Mon Mar 31 20:40:22 GMT 2025 , Edited by admin on Mon Mar 31 20:40:22 GMT 2025
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ECHA (EC/EINECS)
206-070-0
Created by admin on Mon Mar 31 20:40:22 GMT 2025 , Edited by admin on Mon Mar 31 20:40:22 GMT 2025
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NSC
27621
Created by admin on Mon Mar 31 20:40:22 GMT 2025 , Edited by admin on Mon Mar 31 20:40:22 GMT 2025
PRIMARY
PUBCHEM
2723605
Created by admin on Mon Mar 31 20:40:22 GMT 2025 , Edited by admin on Mon Mar 31 20:40:22 GMT 2025
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