| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H17N |
| Molecular Weight | 127.2273 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC[C@@H]1CCCCN1
InChI
InChIKey=NDNUANOUGZGEPO-MRVPVSSYSA-N
InChI=1S/C8H17N/c1-2-5-8-6-3-4-7-9-8/h8-9H,2-7H2,1H3/t8-/m1/s1
(-)-Coniine is a biologically active enantiomer of piperidine alkaloid and nicotinic acetylcholine receptor agonist found in poison hemlock (Conium maculatum L.). (-)-Coniine is teratogenic and its teratogenecity can be explained by the binding, activation, and prolonged desensitization of fetal muscle-type nAChR, which results in the complete inhibition of fetal movement.
CNS Activity
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
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