Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H12Cl2N2.ClH |
Molecular Weight | 267.583 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.ClC1=CC=CC(N2CCNCC2)=C1Cl
InChI
InChIKey=CYQFNNSFAGXCEC-UHFFFAOYSA-N
InChI=1S/C10H12Cl2N2.ClH/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14;/h1-3,13H,4-7H2;1H
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL217 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24827597 |
1160.0 nM [Ki] | ||
Target ID: CHEMBL234 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22632094 |
197.4 nM [Ki] |
PubMed
Title | Date | PubMed |
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N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. | 2003 Jul 7 |
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First structure-activity relationship study on dopamine D3 receptor agents with N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamide structure. | 2005 Dec 15 |
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Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands. | 2005 Jan 3 |
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Synthesis and in vitro antimicrobial study of Schiff base and thiazolidinone of 1-cyclopropyl-6-fluoro-7-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-quinolone. | 2010 Jan-Feb |
Patents
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Code System | Code | Type | Description | ||
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QC5R44625J
Created by
admin on Sat Dec 16 19:52:20 GMT 2023 , Edited by admin on Sat Dec 16 19:52:20 GMT 2023
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2736069
Created by
admin on Sat Dec 16 19:52:20 GMT 2023 , Edited by admin on Sat Dec 16 19:52:20 GMT 2023
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119532-26-2
Created by
admin on Sat Dec 16 19:52:20 GMT 2023 , Edited by admin on Sat Dec 16 19:52:20 GMT 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD