1-(2,3-Dichlorophenyl)piperazine

ClC1=CC=CC(N2CCNCC2)=C1Cl

InChIKey=UDQMXYJSNNCRAS-UHFFFAOYSA-N

InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine D2 receptor 311 Target ID: CHEMBL217 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24827597	Agonist 2752		1160.0 nM [Ki]
Dopamine D3 receptor 97 Target ID: CHEMBL234 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22632094	Agonist 2752		197.4 nM [Ki]

PubMed

Title	Date	PubMed
Synthesis and in vitro antimicrobial study of Schiff base and thiazolidinone of 1-cyclopropyl-6-fluoro-7-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-quinolone.	2010-03-10	20210078
First structure-activity relationship study on dopamine D3 receptor agents with N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamide structure.	2005-12-15	16335915
Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.	2005-01-03	15582454
N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists.	2003-07-07	12798330

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:40:13 GMT 2025` Edited by `admin` on `Mon Mar 31 21:40:13 GMT 2025`
Record UNII	891W3EV0B1
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ARIPIPRAZOLE IMPURITY B [EP IMPURITY]

Preferred Name

English

1-(2,3-Dichlorophenyl)piperazine

Systematic Name

English

N-(2,3-DICHLOROPHENYL)PIPERAZINE

Systematic Name

English

PIPERAZINE, 1-(2,3-DICHLOROPHENYL)-

Systematic Name

English

DCPP

Common Name

English

4-(2,3-DICHLOROPHENYL)PIPERAZINE

Systematic Name

English

Code System Code Type Description

CAS

41202-77-1