1-(2,3-Dichlorophenyl)piperazine

ClC1=CC=CC(N2CCNCC2)=C1Cl

InChIKey=UDQMXYJSNNCRAS-UHFFFAOYSA-N

InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine D2 receptor 297 Target ID: CHEMBL217 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24827597	Agonist 2678		1160.0 nM [Ki]
Dopamine D3 receptor 91 Target ID: CHEMBL234 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22632094	Agonist 2678		197.4 nM [Ki]

PubMed

Title	Date	PubMed
N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists.	2003 Jul 7	12798330
First structure-activity relationship study on dopamine D3 receptor agents with N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamide structure.	2005 Dec 15	16335915
Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.	2005 Jan 3	15582454
Synthesis and in vitro antimicrobial study of Schiff base and thiazolidinone of 1-cyclopropyl-6-fluoro-7-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-quinolone.	2010 Jan-Feb	20210078

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 07:05:45 GMT 2023` Edited by `admin` on `Sat Dec 16 07:05:45 GMT 2023`
Record UNII	891W3EV0B1
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

1-(2,3-Dichlorophenyl)piperazine

Systematic Name

English

ARIPIPRAZOLE IMPURITY B [EP IMPURITY]

Common Name

English

N-(2,3-DICHLOROPHENYL)PIPERAZINE

Systematic Name

English

PIPERAZINE, 1-(2,3-DICHLOROPHENYL)-

Systematic Name

English

DCPP

Common Name

English

4-(2,3-DICHLOROPHENYL)PIPERAZINE

Systematic Name

English

Code System Code Type Description

CAS

41202-77-1