Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C19H20FNO5 |
| Molecular Weight | 361.3642 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C(=O)OCCCCO[N+]([O-])=O)C1=CC(F)=C(C=C1)C2=CC=CC=C2
InChI
InChIKey=DLWSRGHNJVLJAH-UHFFFAOYSA-N
InChI=1S/C19H20FNO5/c1-14(19(22)25-11-5-6-12-26-21(23)24)16-9-10-17(18(20)13-16)15-7-3-2-4-8-15/h2-4,7-10,13-14H,5-6,11-12H2,1H3
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Flurbinitroxybutylester: a novel anti-inflammatory drug has enhanced antithrombotic activity. | 1995 Jul 1 |
|
| Protective effect of NO on gastric lesions and inhibition of expression of gastric inducible NOS by flurbiprofen and its nitro-derivative, nitroflurbiprofen. | 1995 Sep |
|
| Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat. | 2006 Apr |
|
| Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portal hypertension in rats. | 2007 Feb |
|
| Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. | 2010 Nov 23 |
|
| Switching the microglial harmful phenotype promotes lifelong restoration of subtantia nigra dopaminergic neurons from inflammatory neurodegeneration in aged mice. | 2011 Aug |
Patents
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| Code System | Code | Type | Description | ||
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DTXSID30936005
Created by
admin on Fri Dec 15 15:53:00 GMT 2023 , Edited by admin on Fri Dec 15 15:53:00 GMT 2023
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C63702
Created by
admin on Fri Dec 15 15:53:00 GMT 2023 , Edited by admin on Fri Dec 15 15:53:00 GMT 2023
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158836-71-6
Created by
admin on Fri Dec 15 15:53:00 GMT 2023 , Edited by admin on Fri Dec 15 15:53:00 GMT 2023
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Q8ERI3E76F
Created by
admin on Fri Dec 15 15:53:00 GMT 2023 , Edited by admin on Fri Dec 15 15:53:00 GMT 2023
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77428
Created by
admin on Fri Dec 15 15:53:00 GMT 2023 , Edited by admin on Fri Dec 15 15:53:00 GMT 2023
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119387
Created by
admin on Fri Dec 15 15:53:00 GMT 2023 , Edited by admin on Fri Dec 15 15:53:00 GMT 2023
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ACTIVE MOIETY
