FERTIRELIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67009936 | https://www.ncbi.nlm.nih.gov/pubmed/2051323 | https://www.ncbi.nlm.nih.gov/pubmed/7012414

FERTIRELIN is an analog of luteinizing hormone releasing factor. The drug has been used since 1981 in Japan to treat various types of reproductive failure in cattle.

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Gonadotropin-releasing hormone receptor 41 Target ID: CHEMBL1855 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26398856	Agonist 2752		0.7 nM [Ki]

PubMed

PubMed

Title	Date	PubMed
Characterization of 12 GnRH peptide agonists - a kinetic perspective.	2016-01	26398856
New degradation product of des-Gly10-NH2-LH-RH-ethylamide (fertirelin) in aqueous solution.	1991-02	2051323
Therapeutic effects of an analog of luteinizing hormone-releasing hormone (Des-Gly10-LH-RH-ethylamide) on cows with cystic ovary.	1980-08	7012414

Name

Type

Language

TAP 031

Preferred Name

English

FERTIRELIN

Official Name

English

LUTEINIZING HORMONE-RELEASING FACTOR (PIG), 9-(N-ETHYL-L-PROLINAMIDE)-10-DEGLYCINAMIDE-

Common Name

English

TAP-031

Code

English

fertirelin [INN]

Common Name

English

5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TYROSYLGLYCYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE

Common Name

English

FERTIRELIN [JAN]

Common Name

English

FERTIRELIN [MI]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QH01CA91

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NCI_THESAURUS

C1910

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Code System Code Type Description

ChEMBL

CHEMBL2110870

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MERCK INDEX

m5358

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Merck Index

EVMPD

SUB07615MIG

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PUBCHEM

188304

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INN

4675

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SMS_ID

100000080981

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EPA CompTox

DTXSID8057728

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CAS

38234-21-8

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NCI_THESAURUS

C96854

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FDA UNII

Q041AO6T91

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ACTIVE MOIETY


					Q041AO6T91

SALT/SOLVATE (PARENT)


					JD54DU77I8

FERTIRELIN ACETATE