FERTIRELIN

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67009936 | https://www.ncbi.nlm.nih.gov/pubmed/2051323 | https://www.ncbi.nlm.nih.gov/pubmed/7012414

FERTIRELIN is an analog of luteinizing hormone releasing factor. The drug has been used since 1981 in Japan to treat various types of reproductive failure in cattle.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Gonadotropin-releasing hormone receptor 41 Target ID: CHEMBL1855 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26398856	Agonist 2678		0.7 nM [Ki]

PubMed

Title	Date	PubMed
Therapeutic effects of an analog of luteinizing hormone-releasing hormone (Des-Gly10-LH-RH-ethylamide) on cows with cystic ovary.	1980 Aug	7012414
New degradation product of des-Gly10-NH2-LH-RH-ethylamide (fertirelin) in aqueous solution.	1991 Feb	2051323
Characterization of 12 GnRH peptide agonists - a kinetic perspective.	2016 Jan	26398856

Substance Class	Protein Created by `admin` on `Sat Dec 16 00:32:24 GMT 2023` Edited by `admin` on `Sat Dec 16 00:32:24 GMT 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	Q041AO6T91
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FERTIRELIN

Official Name

English

LUTEINIZING HORMONE-RELEASING FACTOR (PIG), 9-(N-ETHYL-L-PROLINAMIDE)-10-DEGLYCINAMIDE-

Common Name

English

TAP-031

Code

English

fertirelin [INN]

Common Name

English

TAP 031

Code

English

5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TYROSYLGLYCYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE

Common Name

English

FERTIRELIN [JAN]

Common Name

English

FERTIRELIN [MI]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QH01CA91