LY-3143921

C[C@]1(NC(=O)C2=CC(=CC=C12)C3=CNN=C3)C4=NC=NC=C4F

InChIKey=KNLVLWZENYQYRT-MRXNPFEDSA-N

InChI=1S/C16H12FN5O/c1-16(14-13(17)7-18-8-19-14)12-3-2-9(10-5-20-21-6-10)4-11(12)15(23)22-16/h2-8H,1H3,(H,20,21)(H,22,23)/t16-/m1/s1

Targets

Primary Target	Pharmacology	Condition	Potency
Cyclin-dependent kinase 7 5 Target ID: P50613 Gene ID: 1022.0 Gene Symbol: CDK7 Target Organism: Homo sapiens (Human) Sources: https://patents.google.com/patent/WO2014143601A1/en	Inhibitor 8297		3.3 nM [IC50]

Name

Type

Language

LY-3143921

Code

English

LY3143921

Code

English

LY3143921 FREE BASE

Code

English

(3R)-3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one

Systematic Name

English

1H-Isoindol-1-one, 3-(5-fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-, (3R)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

81689696

Created by admin on Sat Dec 16 20:10:15 GMT 2023 , Edited by admin on Sat Dec 16 20:10:15 GMT 2023

PRIMARY

CAS

1627696-51-8

Created by admin on Sat Dec 16 20:10:15 GMT 2023 , Edited by admin on Sat Dec 16 20:10:15 GMT 2023

PRIMARY

FDA UNII

PZU987ZDK2

Created by admin on Sat Dec 16 20:10:15 GMT 2023 , Edited by admin on Sat Dec 16 20:10:15 GMT 2023

PRIMARY

ACTIVE MOIETY


					PZU987ZDK2

SALT/SOLVATE (PARENT)


					GM9B9323EH