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Details

Stereochemistry UNKNOWN
Molecular Formula C17H14O4
Molecular Weight 282.2907
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXINDANAC, (+)-

SMILES

OC(=O)C1CCC2=C1C=C(O)C(=C2)C(=O)C3=CC=CC=C3

InChI

InChIKey=XMTKXTUIUKKGIL-UHFFFAOYSA-N
InChI=1S/C17H14O4/c18-15-9-13-11(6-7-12(13)17(20)21)8-14(15)16(19)10-4-2-1-3-5-10/h1-5,8-9,12,18H,6-7H2,(H,20,21)

HIDE SMILES / InChI
Oxindanac, a non-steroidal anti-inflammatory drug, and is a weak cyclooxygenase inhibitor possessed antipyretic activity. This drug is used as a veterinary inflammatory drug. In addition, oxindanac was studied in phase III clinical trials for the treatment of rheumatic disorders. However, this study was discontinued.

Approval Year

PubMed

PubMed

TitleDatePubMed
The anti-oedematous efficacy of oxindanac equals that of paracetamol in acute postoperative inflammation; are weak cyclooxygenase inhibitors more effective than strong inhibitors?
1989
The use of intradermal carrageenan in calves to estimate the dose of oxindanac, a nonsteroidal anti-inflammatory drug.
1993 Oct
High performance liquid chromatography and pharmacokinetics of the non-steroidal anti-inflammatory drug oxindanac in calves.
1994 Jun
Patents

Patents

Sample Use Guides

Eight male volunteers receiving frusemide 40 mg b.d. were also given either oxindanac 300 mg b.d. or placebo in two consecutive periods separated by a treatment-free period, according to a randomized cross-over study design.
Route of Administration: Oral
Name Type Language
OXINDANAC, (+)-
Common Name English
(+)-5-BENZOYL-2,3-DIHYDRO-6-HYDROXY-1H-INDENE-1-CARBOXYLIC ACID
Common Name English
1H-INDENE-1-CARBOXYLIC ACID, 5-BENZOYL-2,3-DIHYDRO-6-HYDROXY-, (+)-
Systematic Name English
Code System Code Type Description
CAS
99910-67-5
Created by admin on Sat Dec 16 10:14:50 GMT 2023 , Edited by admin on Sat Dec 16 10:14:50 GMT 2023
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PUBCHEM
68879
Created by admin on Sat Dec 16 10:14:50 GMT 2023 , Edited by admin on Sat Dec 16 10:14:50 GMT 2023
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FDA UNII
PS75787KJI
Created by admin on Sat Dec 16 10:14:50 GMT 2023 , Edited by admin on Sat Dec 16 10:14:50 GMT 2023
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