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Details

Stereochemistry ACHIRAL
Molecular Formula C9H12O2
Molecular Weight 152.1904
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CUMENE HYDROPEROXIDE

SMILES

CC(C)(OO)C1=CC=CC=C1

InChI

InChIKey=YQHLDYVWEZKEOX-UHFFFAOYSA-N
InChI=1S/C9H12O2/c1-9(2,11-10)8-6-4-3-5-7-8/h3-7,10H,1-2H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
2004-03
Exposure of mouse skin to organic peroxides: subchronic effects related to carcinogenic potential.
2004-03
Cyclodextrin-derived diorganyl tellurides as glutathione peroxidase mimics and inhibitors of thioredoxin reductase and cancer cell growth.
2004-01-01
"In vitro" effect of cumene hydroperoxide on hepatic elongation factor-2 and its protection by melatonin.
2003-12-05
Prevention of brain protein and lipid oxidation elicited by a water-soluble oryzanol enzymatic extract derived from rice bran.
2003-12
A novel and potent biological antioxidant, Kinobeon A, from cell culture of safflower.
2003-11-21
Experimental evidence for the physiological role of bacterial luciferase in the protection of cells against oxidative stress.
2003-11
Measurement of plasma hydroperoxide concentration by FOX-1 assay in conjunction with triphenylphosphine.
2003-11
Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress.
2003-11
Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection.
2003-10-17
Catalysis of oxo transfer to prochiral sulfides by oxovanadium(v) compounds that model the active center of haloperoxidases.
2003-10-06
Effect of carbonate anion on cytochrome P450 2D6-mediated metabolism in vitro: the potential role of multiple oxygenating species.
2003-09-15
Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tert-butyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102.
2003-09-09
[Antioxidant activities of green and black teas determined by the cumene hydroperoxide/hemoglobin.methylene blue method].
2003-09
Unusual atmospheric pressure chemical ionization conditions for detection of organic peroxides.
2003-09
Influence of vitamin C diet supplementation on endogenous antioxidant defences during exhaustive exercise.
2003-09
Determination of lipid peroxides in invertebrates tissues using the Fe(III) xylenol orange complex formation.
2003-08
Separation and identification of DMPO adducts of oxygen-centered radicals formed from organic hydroperoxides by HPLC-ESR, ESI-MS and MS/MS.
2003-08
Role of yeast glutaredoxins as glutathione S-transferases.
2003-06-20
Protective action of CLA against oxidative inactivation of paraoxonase 1, an antioxidant enzyme.
2003-06
Highly enantioselective oxidations of ketene dithioacetals leading to trans bis-sulfoxides.
2003-05-16
UVB-induced activation and internalization of keratinocyte growth factor receptor.
2003-04-24
Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.
2003-03-14
Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics.
2003-03
Modulation of biochemical parameters by Hemidesmus indicus in cumene hydroperoxide-induced murine skin: possible role in protection against free radicals-induced cutaneous oxidative stress and tumor promotion.
2003-03
Determination of organic peroxides by liquid chromatography with on-line post-column ultraviolet irradiation and peroxyoxalate chemiluminescence detection.
2003-02-14
Enhancement of glucose transport in rat thymocytes by different radical sources.
2003-02
Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences.
2003-01-03
Role of the thioredoxin system and the thiol-peroxidases Tpx and Bcp in mediating resistance to oxidative and nitrosative stress in Helicobacter pylori.
2003-01
Asymmetric catalysis with self-organized chiral lanthanum complexes: practical and highly enantioselective epoxidation of alpha,beta-unsaturated ketones.
2003-01
Cytoprotective and anticancer properties of coenzyme Q versus capsaicin.
2003
Assessment of membrane protection by traditional Chinese medicines using a flow cytometric technique: preliminary findings.
2003
Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum.
2002-12-01
Oxidative stress response of rat testis to model prooxidants in vitro and its modulation.
2002-12
Evaluation of the roles that alkyl hydroperoxide reductase and Ohr play in organic peroxide-induced gene expression and protection against organic peroxides in Xanthomonas campestris.
2002-11-29
Evidence from heterologous expression of glutathione S-transferases A and A1 of the plaice (Pleuronectes platessa) that their endogenous role is in detoxification of lipid peroxidation products.
2002-11-01
Combined effects of cadmium and nickel on testicular xenobiotic metabolizing enzymes in rats.
2002-11
Antioxidant balance and free radical generation in vitamin e-deficient mice after dermal exposure to cumene hydroperoxide.
2002-11
The improved synthesis of OPC-29030, a platelet adhesion inhibitor via diastereoselective oxidation of chiral non-racemic sulfide.
2002-11
Complementary DNA cloning, protein expression, and characterization of alpha-class GSTs from Macaca fascicularis liver.
2002-11
Schistosoma mansoni ferredoxin NADP(H) oxidoreductase and its role in detoxification.
2002-10-22
Characteristics of skin wrinkling and dermal changes induced by repeated application of squalene monohydroperoxide to hairless mouse skin.
2002-10-21
Inhibition of lipid peroxidation by S-nitrosoglutathione and copper.
2002-10
Amperometric enzyme electrode for organic peroxides determination prepared from horseradish peroxidase immobilized in poly(vinylferrocenium) film.
2002-10
GSH-dependent peroxidase activity of the rice (Oryza sativa) glutaredoxin, a thioltransferase.
2002-09-06
OhrR, a transcription repressor that senses and responds to changes in organic peroxide levels in Xanthomonas campestris pv. phaseoli.
2002-09
Role of an endoplasmic reticulum Ca(2+)-independent phospholipase A(2) in oxidant-induced renal cell death.
2002-09
Silica-supported, single-site titanium catalysts for olefin epoxidation. A molecular precursor strategy for control of catalyst structure.
2002-07-17
Glutathione S-transferase of the malarial parasite Plasmodium falciparum: characterization of a potential drug target.
2002-05
Flow cytometric determination of lipid peroxidation using fluoresceinated phosphoethanolamine.
2002
Patents
Name Type Language
LUPEROX CU 80
Preferred Name English
CUMENE HYDROPEROXIDE
HSDB  
Systematic Name English
.ALPHA.,.ALPHA.-DIMETHYLBENZYL HYDROPEROXIDE
Systematic Name English
TRIGONOX K 90
Brand Name English
PERCUMYL H
Brand Name English
HYDROPEROXIDE, 1-METHYL-1-PHENYLETHYL
Systematic Name English
CUMENE HYDROPEROXIDE [HSDB]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 176.170
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
Code System Code Type Description
PUBCHEM
6629
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
WIKIPEDIA
CUMENE HYDROPEROXIDE
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
FDA UNII
PG7JD54X4I
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
ECHA (EC/EINECS)
201-254-7
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
MESH
C007164
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
EPA CompTox
DTXSID3024869
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
CHEBI
78673
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
CAS
80-15-9
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY
HSDB
254
Created by admin on Mon Mar 31 22:36:22 GMT 2025 , Edited by admin on Mon Mar 31 22:36:22 GMT 2025
PRIMARY