U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C9H12O2
Molecular Weight 152.1904
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CUMENE HYDROPEROXIDE

SMILES

CC(C)(OO)C1=CC=CC=C1

InChI

InChIKey=YQHLDYVWEZKEOX-UHFFFAOYSA-N
InChI=1S/C9H12O2/c1-9(2,11-10)8-6-4-3-5-7-8/h3-7,10H,1-2H3

HIDE SMILES / InChI

Molecular Formula C9H12O2
Molecular Weight 152.1904
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Flow cytometric determination of lipid peroxidation using fluoresceinated phosphoethanolamine.
2002
Oxidative stress response of rat testis to model prooxidants in vitro and its modulation.
2002 Dec
Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum.
2002 Dec 1
Silica-supported, single-site titanium catalysts for olefin epoxidation. A molecular precursor strategy for control of catalyst structure.
2002 Jul 17
Glutathione S-transferase of the malarial parasite Plasmodium falciparum: characterization of a potential drug target.
2002 May
Combined effects of cadmium and nickel on testicular xenobiotic metabolizing enzymes in rats.
2002 Nov
Antioxidant balance and free radical generation in vitamin e-deficient mice after dermal exposure to cumene hydroperoxide.
2002 Nov
The improved synthesis of OPC-29030, a platelet adhesion inhibitor via diastereoselective oxidation of chiral non-racemic sulfide.
2002 Nov
Complementary DNA cloning, protein expression, and characterization of alpha-class GSTs from Macaca fascicularis liver.
2002 Nov
Evaluation of the roles that alkyl hydroperoxide reductase and Ohr play in organic peroxide-induced gene expression and protection against organic peroxides in Xanthomonas campestris.
2002 Nov 29
Inhibition of lipid peroxidation by S-nitrosoglutathione and copper.
2002 Oct
Amperometric enzyme electrode for organic peroxides determination prepared from horseradish peroxidase immobilized in poly(vinylferrocenium) film.
2002 Oct
OhrR, a transcription repressor that senses and responds to changes in organic peroxide levels in Xanthomonas campestris pv. phaseoli.
2002 Sep
Role of an endoplasmic reticulum Ca(2+)-independent phospholipase A(2) in oxidant-induced renal cell death.
2002 Sep
GSH-dependent peroxidase activity of the rice (Oryza sativa) glutaredoxin, a thioltransferase.
2002 Sep 6
Evidence from heterologous expression of glutathione S-transferases A and A1 of the plaice (Pleuronectes platessa) that their endogenous role is in detoxification of lipid peroxidation products.
2002 Sep-Dec
Schistosoma mansoni ferredoxin NADP(H) oxidoreductase and its role in detoxification.
2002 Sep-Oct
Cytoprotective and anticancer properties of coenzyme Q versus capsaicin.
2003
Assessment of membrane protection by traditional Chinese medicines using a flow cytometric technique: preliminary findings.
2003
UVB-induced activation and internalization of keratinocyte growth factor receptor.
2003 Apr 24
Determination of lipid peroxides in invertebrates tissues using the Fe(III) xylenol orange complex formation.
2003 Aug
Separation and identification of DMPO adducts of oxygen-centered radicals formed from organic hydroperoxides by HPLC-ESR, ESI-MS and MS/MS.
2003 Aug
Prevention of brain protein and lipid oxidation elicited by a water-soluble oryzanol enzymatic extract derived from rice bran.
2003 Dec
"In vitro" effect of cumene hydroperoxide on hepatic elongation factor-2 and its protection by melatonin.
2003 Dec 5
Enhancement of glucose transport in rat thymocytes by different radical sources.
2003 Feb
Determination of organic peroxides by liquid chromatography with on-line post-column ultraviolet irradiation and peroxyoxalate chemiluminescence detection.
2003 Feb 14
Role of the thioredoxin system and the thiol-peroxidases Tpx and Bcp in mediating resistance to oxidative and nitrosative stress in Helicobacter pylori.
2003 Jan
Asymmetric catalysis with self-organized chiral lanthanum complexes: practical and highly enantioselective epoxidation of alpha,beta-unsaturated ketones.
2003 Jan
Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences.
2003 Jan 3
Characteristics of skin wrinkling and dermal changes induced by repeated application of squalene monohydroperoxide to hairless mouse skin.
2003 Jul-Aug
Protective action of CLA against oxidative inactivation of paraoxonase 1, an antioxidant enzyme.
2003 Jun
Role of yeast glutaredoxins as glutathione S-transferases.
2003 Jun 20
Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics.
2003 Mar
Modulation of biochemical parameters by Hemidesmus indicus in cumene hydroperoxide-induced murine skin: possible role in protection against free radicals-induced cutaneous oxidative stress and tumor promotion.
2003 Mar
Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.
2003 Mar 14
Highly enantioselective oxidations of ketene dithioacetals leading to trans bis-sulfoxides.
2003 May 16
Experimental evidence for the physiological role of bacterial luciferase in the protection of cells against oxidative stress.
2003 Nov
Measurement of plasma hydroperoxide concentration by FOX-1 assay in conjunction with triphenylphosphine.
2003 Nov
Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress.
2003 Nov
A novel and potent biological antioxidant, Kinobeon A, from cell culture of safflower.
2003 Nov 21
Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection.
2003 Oct 17
Catalysis of oxo transfer to prochiral sulfides by oxovanadium(v) compounds that model the active center of haloperoxidases.
2003 Oct 6
[Antioxidant activities of green and black teas determined by the cumene hydroperoxide/hemoglobin.methylene blue method].
2003 Sep
Unusual atmospheric pressure chemical ionization conditions for detection of organic peroxides.
2003 Sep
Influence of vitamin C diet supplementation on endogenous antioxidant defences during exhaustive exercise.
2003 Sep
Effect of carbonate anion on cytochrome P450 2D6-mediated metabolism in vitro: the potential role of multiple oxygenating species.
2003 Sep 15
Free radical scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tert-butyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102.
2003 Sep 9
Cyclodextrin-derived diorganyl tellurides as glutathione peroxidase mimics and inhibitors of thioredoxin reductase and cancer cell growth.
2004 Jan 1
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
2004 Mar
Exposure of mouse skin to organic peroxides: subchronic effects related to carcinogenic potential.
2004 Mar
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 09:17:11 GMT 2023
Edited
by admin
on Sat Dec 16 09:17:11 GMT 2023
Record UNII
PG7JD54X4I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CUMENE HYDROPEROXIDE
HSDB  
Systematic Name English
.ALPHA.,.ALPHA.-DIMETHYLBENZYL HYDROPEROXIDE
Systematic Name English
TRIGONOX K 90
Brand Name English
PERCUMYL H
Brand Name English
LUPEROX CU 80
Brand Name English
HYDROPEROXIDE, 1-METHYL-1-PHENYLETHYL
Systematic Name English
CUMENE HYDROPEROXIDE [HSDB]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 176.170
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
Code System Code Type Description
PUBCHEM
6629
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
WIKIPEDIA
CUMENE HYDROPEROXIDE
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
FDA UNII
PG7JD54X4I
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
ECHA (EC/EINECS)
201-254-7
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
MESH
C007164
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
EPA CompTox
DTXSID3024869
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
CHEBI
78673
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
CAS
80-15-9
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY
HSDB
254
Created by admin on Sat Dec 16 09:17:11 GMT 2023 , Edited by admin on Sat Dec 16 09:17:11 GMT 2023
PRIMARY