| Stereochemistry | ABSOLUTE |
| Molecular Formula | C11H17NO.ClH |
| Molecular Weight | 215.72 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.C[C@H]([C@@H](O)C1=CC=CC=C1)N(C)C
InChI
InChIKey=NTCYWJCEOILKNG-FOKYBFFNSA-N
InChI=1S/C11H17NO.ClH/c1-9(12(2)3)11(13)10-7-5-4-6-8-10;/h4-9,11,13H,1-3H3;1H/t9-,11-;/m1./s1
Methylephedrine is one of the ephedra alkaloids that is found in varying amounts in different species of the plant genus Ephedra. Methylephedrine is a popular antitussive, bronchodilator, analgesic, antipyretic, and widely used mixed with other drugs in preparations for treatment of the common cold. N-Methylephedrine, its salts, optical isomers, and salts of optical isomers are in FDA list of Exempt chemical mixtures.
CNS Activity
Originator
Approval Year
PubMed
Patents
Sample Use Guides
Take 0.25-0.5 g (25-50 mg of the active ingredient) at a time, 3 times daily
Route of Administration:
Oral
l-MEP inhibited the twitch response at high concentrations (3 x 10(-5)-10(-3) M). On the other hand, d-MEP showed the potentiation of twitch response, and competitively antagonized the twitch-inhibitory effect of clonidine (10(-9)-10(-6) M) with the pA2 value of 4.3 in the presence of prazosin.
SUBSTANCE RECORD
