Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H14N.Li |
| Molecular Weight | 107.123 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Li+].CC(C)[N-]C(C)C
InChI
InChIKey=ZCSHNCUQKCANBX-UHFFFAOYSA-N
InChI=1S/C6H14N.Li/c1-5(2)7-6(3)4;/h5-6H,1-4H3;/q-1;+1
DescriptionCurator's Comment: description was created based on several sources, including:
http://www.fmclithium.com/Portals/FMCLithium/content/docs/DataSheet/QS-PDS-047%20r1.pdf
Curator's Comment: description was created based on several sources, including:
http://www.fmclithium.com/Portals/FMCLithium/content/docs/DataSheet/QS-PDS-047%20r1.pdf
Lithium diisopropylamide (LDA) is a prominent reagent used in organic synthesis. It is strong, low-nucleophilic base for e.g. enolisations. Corrosive to the eyes (may cause blindness), skin, mucous membranes and upper respiratory tract. Inhalation of vapors may cause dizziness, nausea, anesthesia, numbness, motor weakness in fingers and toes, incoordination, and headache.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Lithium Diisopropylamide: Nonequilibrium Kinetics and Lessons Learned about Rate Limitation. | 2017-05-05 |
|
| Sodium Diisopropylamide in N,N-Dimethylethylamine: Reactivity, Selectivity, and Synthetic Utility. | 2016-11-18 |
|
| One-Pot Halogen Dance/Negishi Coupling of Dibromothiophenes for Regiocontrolled Synthesis of Multiply Arylated Thiophenes. | 2016-11-07 |
|
| Lithium Enolates Derived from Pyroglutaminol: Mechanism and Stereoselectivity of an Azaaldol Addition. | 2016-08-17 |
|
| Lithium diisopropylamide: solution kinetics and implications for organic synthesis. | 2007 |
Patents
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Systematic Name | English | ||
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OL028KIW1I
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LITHIUM DIISOPROPYLAMIDE
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DTXSID6063305
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2724682
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m4485
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4111-54-0
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223-893-0
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SUBSTANCE RECORD
