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Details

Stereochemistry RACEMIC
Molecular Formula C3H7O6P.Mn
Molecular Weight 224.9959
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MANGANESE RAC-GLYCERYL-1-PHOSPHATE

SMILES

[Mn++].OCC(O)COP([O-])([O-])=O

InChI

InChIKey=CQQGLXZHXDHSJD-UHFFFAOYSA-L
InChI=1S/C3H9O6P.Mn/c4-1-3(5)2-9-10(6,7)8;/h3-5H,1-2H2,(H2,6,7,8);/q;+2/p-2

HIDE SMILES / InChI
Manganese citrate is generally recognized as safe direct food additive. Manganese citrate complex has being used in the determination of liver enzyme activities in the aging process and following treatment with aminoethylisothiuronium bromide hydrobromide (AET).

Approval Year

Targets

Targets

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Manganese is used for prevention and treatment of manganese deficiency, a condition in which the body doesn’t have enough manganese.
Primary
Unknown

Approved Use

Manganese is used for weak bones (osteoporosis).
Palliative
Unknown

Approved Use

Early research suggests that taking manganese along with calcium helps improve symptoms of PMS, including pain, crying, loneliness, anxiety, restlessness, irritability, mood swings, depression, and tension.
Curative
MANGANESE SULFATE

Approved Use

Manganese Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for Total Parenteral Nutrition (TPN). Administration helps to maintain plasma levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
Primary
MANGANESE SULFATE

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Cytochrome oxidase determination using a manganese citrate complex.
1970
Metabolism of l-Tyrosine to 4-Hydroxybenzaldehyde and 3-Bromo-4-Hydroxybenzaldehyde by Chloroplast-containing Fractions of Odonthalia floccosa (Esp.) Falk.
1979 Dec
Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure.
1993 Jul
Manganese citrate chemistry: syntheses, spectroscopic studies, and structural characterizations of novel mononuclear, water-soluble manganese citrate complexes.
2000 Sep 4
Glutamate/aspartate transporter (GLAST), taurine transporter and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate or manganese sulfate.
2002 Sep
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism.
2005 Mar
Persistent alterations in biomarkers of oxidative stress resulting from combined in utero and neonatal manganese inhalation.
2005 May
CsR(R(6)CoI(12))2 (R = Gd, Er) and (CeI)0.26(Ce(6)MnI(9))2: two new structure types featuring R(6)Z clusters.
2006 Nov 27
Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity.
2007 Jun
Controlled Synthesis of Hollow Manganese Oxide Nanocrystals.
2016 Feb
Top-Down Strategy to Synthesize Mesoporous Dual Carbon Armored MnO Nanoparticles for Lithium-Ion Battery Anodes.
2017 Apr 12
Intramolecular Aminoalkoxylation of Unfunctionalized Olefins via Intramolecular Iodoamination and Aziridinium Ion Ring-Opening Sequence.
2017 Apr 7
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Curator's Comment: In vitro cytotoxicity of manganese oxide (MnO) using live/dead cell assay, lactate dehydrogenase assay, and reactive oxygen species detection with variation of the concentration of nanoparticles (5-500 ug/ml), incubation time (18-96 h), and different human cell lines (lung adenocarcinoma, breast cancer cells, and glioblastoma cells) was studied. The cytotoxic effect was negligible for 18 h incubation even at highest concentration of 500 ug/ml MnO nanoparticle.
Unknown
Name Type Language
MANGANESE RAC-GLYCERYL-1-PHOSPHATE
Common Name English
MANGANESE(2+) 2,3-DIHYDROXYPROPYL PHOSPHATE
Systematic Name English
RAC-GLYCERO-1-PHOSPHATE, MANGANESE SALT
Common Name English
1,2,3-PROPANETRIOL, 1-(DIHYDROGEN PHOSPHATE), MANGANESE(2+) SALT (1:1)
Common Name English
MANGANESE GLYCEROPHOSPHATE ANHYDROUS
Common Name English
MANGANESE GLYCERYL-1-PHOSPHATE
Common Name English
1,2,3-PROPANETRIOL, 1-(DIHYDROGEN PHOSPHATE), MANGANESE(2+) SALT (1:1), (±)-
Common Name English
Code System Code Type Description
PUBCHEM
11579475
Created by admin on Fri Dec 15 16:24:09 GMT 2023 , Edited by admin on Fri Dec 15 16:24:09 GMT 2023
PRIMARY
FDA UNII
O8CNB3NY0U
Created by admin on Fri Dec 15 16:24:09 GMT 2023 , Edited by admin on Fri Dec 15 16:24:09 GMT 2023
PRIMARY
EPA CompTox
DTXSID60931725
Created by admin on Fri Dec 15 16:24:09 GMT 2023 , Edited by admin on Fri Dec 15 16:24:09 GMT 2023
PRIMARY
CAS
143007-66-3
Created by admin on Fri Dec 15 16:24:09 GMT 2023 , Edited by admin on Fri Dec 15 16:24:09 GMT 2023
PRIMARY
EVMPD
SUB31715
Created by admin on Fri Dec 15 16:24:09 GMT 2023 , Edited by admin on Fri Dec 15 16:24:09 GMT 2023
PRIMARY