AZEPEXOLE DIHYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H15N3O.2ClH
Molecular Weight	254.157
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.Cl.CCN1CCC2=C(CC1)N=C(N)O2

InChI

InChIKey=HBLPYIOKPJVFQW-UHFFFAOYSA-N

InChI=1S/C9H15N3O.2ClH/c1-2-12-5-3-7-8(4-6-12)13-9(10)11-7;;/h2-6H2,1H3,(H2,10,11);2*1H

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2866788 | https://www.ncbi.nlm.nih.gov/pubmed/6814471

Azepexole (or previously known as B-HT 933), a selective alpha 2-adrenoceptor agonist that was studied for the man with physiological tremor. It was shown that the drug produced sedation compared to placebo but not when compared to pre-treatment values. Some studies also have revealed the anti-tussive and antihypertensive properties of azepexole.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor alpha-2 113 Target ID: CHEMBL2095158 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2547487 \| https://www.ncbi.nlm.nih.gov/pubmed/1970494 \| https://www.ncbi.nlm.nih.gov/pubmed/7541362	Agonist 2678

PubMed

Title	Date	PubMed
		252159909

Patents

Sample Use Guides

In Vivo Use Guide

azepexole 10 mg

Route of Administration: Oral

Name

Type

Language

AZEPEXOLE DIHYDROCHLORIDE

Common Name

English

NSC-310831

Code

English

4H-OXAZOLO(4,5-D)AZEPIN-2-AMINE, 6-ETHYL-5,6,7,8-TETRAHYDRO-, HYDROCHLORIDE (1:2)

Systematic Name

English

B-HT-933 DIHYDROCHLORIDE

Common Name

English

Code System Code Type Description

CAS

36067-72-8