PROSTALENE

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H36O5
Molecular Weight	380.5182
Optical Activity	( + / - )
Defined Stereocenters	5 / 5
E/Z Centers	3
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC[C@@](C)(O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=C=CCCC(=O)OC

InChI

InChIKey=GNIYHUSSKSFYBD-MFZPGRHISA-N

InChI=1S/C22H36O5/c1-4-5-10-14-22(2,26)15-13-18-17(19(23)16-20(18)24)11-8-6-7-9-12-21(25)27-3/h7-8,13,15,17-20,23-24,26H,4-5,9-12,14,16H2,1-3H3/b15-13+/t6?,17-,18-,19+,20-,22-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=522.2012 | https://www.drugs.com/international/prostalene.html

Prostalene is an analogue of prostaglandin PGF-2 alpha. It is used for the control of estrus in mares.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
prostaglandin F receptor (FP) 1 Target ID: 1.00009712E8 Gene Symbol: PTGFR Sources: https://www.ncbi.nlm.nih.gov/pubmed/550139 \| https://www.ncbi.nlm.nih.gov/pubmed/289794	Agonist 2678

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pregnancy 65 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16726434 https://www.ncbi.nlm.nih.gov/pubmed/289794 https://www.ncbi.nlm.nih.gov/pubmed/1049488	Preventing		Approved 8429	Synchrocept B Approved Use Indications for use: For the control of estrus in mares.

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Conditions of use in horses --(1) Amount. Administer 5 micrograms per kilogram of body weight as a single subcutaneous injection.

Route of Administration: Other

In Vitro Use Guide

Unknown

Name

Type

Language

PROSTALENE

Official Name

English

PROSTALENE [MART.]

Common Name

English

SYNCHROCEPT

Brand Name

English

PROSTALENE [USAN]

Common Name

English

(±)-METHYL 7-((1R*,2R*,3R*,5S*)-3,5-DIHYDROXY-2-((E)-3-HYDROXY-3-METHYL-1-OCTENYL)CYCLOPENTYL)-4,5-HEPTADIENOATE

Systematic Name

English

prostalene [INN]

Common Name

English

RS-9390

Code

English

PROSTA-4,5,13-TRIEN-1-OIC ACID, 9,11,15-TRIHYDROXY-15-METHYL-, METHYL ESTER, (9.ALPHA.,11.ALPHA.,13E,15R)-, (±)-

Common Name

English

PROSTALENE [GREEN BOOK]

Common Name

English

PROSTALENE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78568

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

CFR

21 CFR 522.2012

Created by admin on Fri Dec 15 16:17:25 GMT 2023 , Edited by admin on Fri Dec 15 16:17:25 GMT 2023

Code System Code Type Description

ChEMBL

CHEMBL2105317

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

PRIMARY

NCI_THESAURUS

C76903

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

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CAS

54120-61-5

Created by admin on Fri Dec 15 16:17:25 GMT 2023 , Edited by admin on Fri Dec 15 16:17:25 GMT 2023

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FDA UNII

O02SWY8981

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

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MERCK INDEX

m9261

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

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Merck Index

DRUG BANK

DB11454

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

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EPA CompTox

DTXSID50102160

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

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EVMPD

SUB10133MIG

Created by admin on Fri Dec 15 16:17:25 GMT 2023 , Edited by admin on Fri Dec 15 16:17:25 GMT 2023

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ECHA (EC/EINECS)

258-984-4

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

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INN

3873

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

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PUBCHEM

6436031

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

PRIMARY

SMS_ID

100000080832

Created by admin on Fri Dec 15 16:17:26 GMT 2023 , Edited by admin on Fri Dec 15 16:17:26 GMT 2023

PRIMARY

ACTIVE MOIETY


					O02SWY8981

PROSTALENE

Details

SMILES

InChI

DescriptionSources: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=522.2012 | https://www.drugs.com/international/prostalene.html

Originator

Approval Year

Targets

Conditions

Approved Use

PubMed

Patents

Sample Use Guides

Description
Sources: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=522.2012 | https://www.drugs.com/international/prostalene.html